2009 Fiscal Year Final Research Report
Single-molecule tracking study of the formation and functions of raft molecular complexes
| Project/Area Number |
17081010
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | Kyoto University |
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Principal Investigator |
KUSUMI Akihiro Kyoto University, 物質-細胞統合システム拠点, 教授 (50169992)
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| Project Period (FY) |
2005 – 2009
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| Keywords | IgE-Fc受容体 / 可塑的ナノドメイン / 細胞膜 / 1分子追跡・1分子イメジング |
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| Research Abstract |
Intracellular lipid-anchored signaling molecules, Gαi2, Lyn, and PLCγ, were found to be transiently recruited to ligand-induced CD59-cluster rafts, leading to intracellular IP3-calcium signaling.
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