2007 Fiscal Year Final Research Report Summary
Population based study of genetic risk and gene-environment interaction in lifestyle-related diseases including coronary artery diseases(KING Study)
| Project/Area Number |
17209021
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hygiene
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| Research Institution | Aichi Gakuin University (2006-2007)
Nagoya University (2005) |
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Principal Investigator |
YOKOTA Mitsuhiro Aichi Gakuin University, School of Dentistry, Professor (50201851)
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| Co-Investigator(Kenkyū-buntansha) |
NAGATA Kohzo Nagoya University, School of Medicine, Assistant Professor (20378227)
OBATA Koji Aichi-Gakuin University, School of Dentistry, Associate Professor (40378229)
IZAWA Hideo Nagoya University, Graduate School of Medicine, Lecturer (80402569)
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| Project Period (FY) |
2005 – 2007
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| Keywords | Investigation of Genetic Risk of Cardiovascular Di / King Study / Cohort Study / Lifestyle Related-Disease / Genome-Wide and Candidate Gene Association Study / Odds Ratio / Susceptibility Gene / DNA Bank |
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| Research Abstract |
Atherosclerotic CAD is a major health problem around the world. The CAD is believed to be multifactorial and to result from many genes, each with a relatively small effect, working alone or in combination with modifier genes and/or environmental factors.
Despite the years of research, the genetic basis of CAD or myocardial infarction (MI) remains to be fully elucidated. In this paper, we highlight emerging knowledge and paradigms from a number of technologies to identify susceptibility genes to MI.
The coronary artery disease (CAD) results from the combination of multiple genetic and environmental factors. We describe the genetic approaches researchers are using to advance understanding and preventing of CAD. The genetic identification of the future development of risk factors will lead to genome-informed tailored prevention
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Research Products
(52 results)
