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2008 Fiscal Year Final Research Report

Research on exploration of arid land in North Africa

Research Project

  • PDF
Project/Area Number 17255011
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Boundary agriculture
Research InstitutionUniversity of Tsukuba

Principal Investigator

ISODA Hiroko  University of Tsukuba, 大学院・生命環境科学研究科, 教授 (00375429)

Co-Investigator(Kenkyū-buntansha) ABE Yukuo  筑波大学, 名誉教授 (70015808)
HIGASHI Teruo  筑波大学, 大学院・生命環境科学研究科, 教授 (20094170)
NAKAMURA Touru  筑波大学, 大学院・生命環境科学研究科, 教授
FUJIMURA Tatsuhito  筑波大学, 大学院・生命環境科学研究科, 教授 (70292513)
NAGAKI Masakazu  筑波大学, 大学院・生命環境科学研究科, 教授 (90003144)
MIYAZAKI Hitoshi  筑波大学, 大学院・生命環境科学研究科, 教授 (40183636)
NAKAMURA Kouji  筑波大学, 大学院・生命環境科学研究科, 准教授 (40212097)
SHIGEMORI Hideyuki  筑波大学, 大学院・生命環境科学研究科, 教授 (70202108)
Project Period (FY) 2005 – 2008
Keywords北アフリカ / 生物資源 / 乾燥地 / 環境分析
Research Abstract

北アフリカ乾燥地域を対象に生物資源・遺伝子資源関連情報収集・機能解析、生態環境調査を行なった。その結果、百数種類のアロマ植物、7種類のオリーブオイルおよびオリーブ葉抽出物の抗ガン、抗アレルギー、神経保護、美白、育毛活性を発見した。研究成果関連学術論文発表35編、国外・国内特許出願6件、国際・国内学会発表25件、シンポジウム開催1回、現地調査13回、データベース構築・公開などの活動を行った。

  • Research Products

    (50 results)

All 2009 2008 2007 2006 Other

All Journal Article (33 results) (of which Peer Reviewed: 29 results) Presentation (10 results) Remarks (1 results) Patent(Industrial Property Rights) (6 results) (of which Overseas: 1 results)

  • [Journal Article] Anti-neuronal Stress Effect of Rosmarinus officinalis Extract2009

    • Author(s)
      A.E. Omri, J.K. Han, M. B. Abdrabbah. H. Isoda
    • Journal Title

      Journal of Arid Land Studies (inpress)

    • Peer Reviewed
  • [Journal Article] Effect of Mediterranean Medicinal Plant Extracts on Melanogenesis Regulation2009

    • Author(s)
      K. Matsuyama, H. Shigemori, H. Isoda(Total 7 authors, No. 6 and No. 7)
    • Journal Title

      Journal of Arid Land Studies (inpress)

    • Peer Reviewed
  • [Journal Article] Anti-proliferative and Apoptotic Effects of Oleuropein and Hydroxytyrosol on Human Breast Cancer MCT-7 Cells2009

    • Author(s)
      J. Han, T.P.N. Talorete, P. Yamada, H. Isoda
    • Journal Title

      Journal of Arid Land Studies (inpress)

    • Peer Reviewed
  • [Journal Article] Advanced Processing of Useful Food Material for Establishment of Regional Development Model in Arid Area2009

    • Author(s)
      H. Isoda
    • Journal Title

      Journal of Arid Land Studies (inpress)

    • Peer Reviewed
  • [Journal Article] Interaction Between Tight Junction Regulation and Integrin Scaffold Protein Expression on the Human Intestinal Caco-2 Cells2009

    • Author(s)
      R. Uchida, J. Han, H. Isoda
    • Journal Title

      Journal of Arid Land Studies (inpress)

    • Peer Reviewed
  • [Journal Article] Environmental Risk Assessment of Water Resources in Arid and Semi-arid Lands Using Bioassays Systems2009

    • Author(s)
      F.B. Fredj, H. Isoda(Total 7 authors, No. 7)
    • Journal Title

      Journal of Arid Land Studies (inpress)

    • Peer Reviewed
  • [Journal Article] Anti-allergic Effect of Acteoside Derived from Arid Land Plant Cistanche tubulosa2009

    • Author(s)
      R. Iijima, P. Yamada, J. Han, H. Shigemori, H. Isoda
    • Journal Title

      Journal of Arid Land Studies (inpress)

    • Peer Reviewed
  • [Journal Article] Hair growth regulation by the extract of aromatic plant Erica multiflora2009

    • Author(s)
      K. Mitsuko, J. Han, M.E. Kchouk, H. Isoda
    • Journal Title

      Journal of Natural Medicines (inpress)

    • Peer Reviewed
  • [Journal Article] Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells2009

    • Author(s)
      J. Han, T.P.N. Talorete, P. Yamada, H. Isoda
    • Journal Title

      Cytotechnology 59

      Pages: 45-53

    • Peer Reviewed
  • [Journal Article] 北アフリカの森林帯概説~垂直分布水平分布~2009

    • Author(s)
      中村徹、礒田博子(全4名、1番目と2番目)
    • Journal Title

      沙漠研究 18(4)

      Pages: 161-165

  • [Journal Article] チュニジアのオリーブ栽培における土壌中の金属元素量とオリーブオイル中のフェノール性化合物量2009

    • Author(s)
      東照雄、礒田博子(全5名、1番目と5番目)
    • Journal Title

      沙漠研究 18(4)

      Pages: 167-170

  • [Journal Article] 未開拓生物資源由来の機能性物質の探索2009

    • Author(s)
      繁森英幸、礒田博子
    • Journal Title

      沙漠研究 18(4)

      Pages: 177-181

  • [Journal Article] 北アフリカ資源植物のデータベース化2009

    • Author(s)
      川田清和、A.E. OMRI、礒田博子
    • Journal Title

      沙漠研究 18(4)

      Pages: 189-192

  • [Journal Article] Indole Acetic Acid Falcarindiol Ester Induces Granulocytic Differentiation of Human Leukemia Cell Line HL-602009

    • Author(s)
      S. Tsolmon, H. Shigemori, H. Isoda (Total 5 authors, No. 4 and No. 5)
    • Journal Title

      S. Planta Medica 75

      Pages: 49-54

    • Peer Reviewed
  • [Journal Article] 農村地域の自立活性化と「地産地消」2009

    • Author(s)
      永木正和
    • Journal Title

      農村計画学会誌(農村計画学会) 27

      Pages: 355-358

    • Peer Reviewed
  • [Journal Article] Lipid-lowering and antioxidant effects of hydroxytyrosol and its triacetylated derivative recovered from olive tree leaves in cholesterol fed rats2008

    • Author(s)
      H. Jemai, H. Isoda (Total 7 authors, No. 6)
    • Journal Title

      Journal of Agricultural and Food Chemistry 56

      Pages: 2630-2636

    • Peer Reviewed
  • [Journal Article] Inhibitory effect of various Tunisian olive oils on chemical mediator release and cytokine production by basophilic cells2008

    • Author(s)
      P. Yamada, M. Zarrouk, K. Kawasaki, H. Isoda
    • Journal Title

      Journal of Ethnopharmacology 116

      Pages: 279-287

    • Peer Reviewed
  • [Journal Article] T. Naganuma. Virgibacillus salarius sp. nov., a novel halophilic bacterium isolated from a Saharan salt lake2008

    • Author(s)
      N.P. Hua, H.C. Amel, R.H. Vreeland, H. Isoda
    • Journal Title

      International Journal of Systematic and Evolutionary Microbiology 58

      Pages: 2409-2414

    • Peer Reviewed
  • [Journal Article] Stress response of mammalian cells incubated with landfill leachate2008

    • Author(s)
      T.P.N. Talorete, H. Isoda (Total 6 authors, No. 6)
    • Journal Title

      Environmental Toxicology and Chemistry 27(5)

      Pages: 1084-1092

    • Peer Reviewed
  • [Journal Article] 21世紀型バイオプロスペクティング2008

    • Author(s)
      宮崎均、礒田博子、安部征雄、中村幸治
    • Journal Title

      化学と生物 43(7)

      Pages: 482-485

    • Peer Reviewed
  • [Journal Article] Assessment of estrogenic activity in Tunisian water and wastewater by E-screen assay2007

    • Author(s)
      A. Liman, Y. Abe, A. Ghrabi, H. Isoda (Total 8 authors, No. 3 and No. 8)
    • Journal Title

      Environmental Sciences 14

      Pages: 43-52

    • Peer Reviewed
  • [Journal Article] Toxicity assessment of wastewater by proteomics analysis2007

    • Author(s)
      J. Han, H. Isoda (Total 5 authors, No. 5)
    • Journal Title

      Environmental Sciences 14

      Pages: 35-41

    • Peer Reviewed
  • [Journal Article] Antimelanogenesis effect of Tunisian herb Thymelaea hirsute extract on B16 murine melanoma cells2007

    • Author(s)
      M. Kawano, T. Morio, H. Shigemori, H. Isoda (Total 8 authors, No. 7 and No. 8)
    • Journal Title

      Experimental Dermatology 16

      Pages: 977-984

    • Peer Reviewed
  • [Journal Article] Inhibitory effect of fulvic acid extracted from Canadian Sphagnum peat on chemical mediator release by RBL-2H3 and KU812 cells, Bioscience2007

    • Author(s)
      P. Yamada, H. Isoda, J. Han, T.P.N. Talorete, Y. Abe
    • Journal Title

      Biotechnology, Biochemistry

      Pages: 149-156

    • Peer Reviewed
  • [Journal Article] Tunisian Gerboui olive leaf extract induces growth inhibition and differentiation of human leukemia HL-60 cells2007

    • Author(s)
      L .Abaza, H. Isoda (Total 6 authors, No. 6)
    • Journal Title

      Bioscience, Biotechnology, Biochemistry

      Pages: 149-156

    • Peer Reviewed
  • [Journal Article] Screening of Antiallergy Compounds from Natural Resourced2006

    • Author(s)
      P. Yamada, H. Isoda
    • Journal Title

      ournal of Arid Land Studies 15(4)

      Pages: 439-442

    • Peer Reviewed
  • [Journal Article] Methods for Searching and Evaluating effective Hair Growth Regulation Factors from Tunisian Samples2006

    • Author(s)
      M. Kawano, T. Imamura, H. Isoda
    • Journal Title

      Journal of Arid Land Studies 15(4)

      Pages: 443-446

    • Peer Reviewed
  • [Journal Article] Evaluation of a domestic wastewater treatment system for arid and semiarid lands by in vitro bioassays2006

    • Author(s)
      F. Ben Fredj, Y. Abe, H. Isoda (Total 5 authors, No. 3 and No. 5)
    • Journal Title

      Journal of Arid Land Studies 16(3)

      Pages: 149-156

    • Peer Reviewed
  • [Journal Article] Study of salt removal with evaporation drainage method2006

    • Author(s)
      M. Majed, A. Zreig, Y. Abe, H. Isoda
    • Journal Title

      Canadian Biosystem Engineering 48

      Pages: 23-28

    • Peer Reviewed
  • [Journal Article] The auto-regulative capability of pitcher irrigation system2006

    • Author(s)
      M. Majed, A. Zreig, Y. Abe, H. Isoda
    • Journal Title

      Agricultural Water Management 85

      Pages: 272-278

    • Peer Reviewed
  • [Journal Article] Stand biomass estimation method by canopy coverage for application to remote sensing in an arid area of western Australia2006

    • Author(s)
      H. Suganuma, Y. Abe (Total 7 authors, No. 2)
    • Journal Title

      Forest Ecology and Management 222

      Pages: 75-87

    • Peer Reviewed
  • [Journal Article] Gene Expression of ADP-glucose Pyrophosphorylase and Starch Contents in Rice Cultured Cells are Cooperatively Regulated by Sucrose and ABA2006

    • Author(s)
      T. Akihiro, K. Mizuno, T. Fujimura
    • Journal Title

      Plant Cell Physiol 46(6)

      Pages: 937-946

    • Peer Reviewed
  • [Journal Article] Concentration and loading of several pesticides in water, suspended solids and sediment during ordinary water discharge in Sugaomarsh, Ibaraki prefecture, Japan2006

    • Author(s)
      T. Kawakami, T. Higashi (Total 7 authors, No. 7)
    • Journal Title

      J.Pestic.Sci 31

      Pages: 6-13

    • Peer Reviewed
  • [Presentation] Towards effective and sustainable utilization of bioresource in North Africa, Thirt international symposium on medicinal and aromatic plants2009

    • Author(s)
      T. Morio, J. Han, P. Yamada, H. Isoda
    • Organizer
      SIPAM
    • Place of Presentation
      Tunisia Sfak
    • Year and Date
      20090326-28
  • [Presentation] nhibitory effect of new daphnane diterpenoids from Tunisian Thymelaea hirsuta on melanogenesis2008

    • Author(s)
      M. Orlina-Villareal, Y. Miyamae, J. Han, P. Yamada, H. Shigemori, H. Isoda
    • Organizer
      JAACT
    • Place of Presentation
      Fukuoka
    • Year and Date
      20081124-27
  • [Presentation] Environmental Risk Assessment of Water Resources in Arid and Semi-arid Lands Using Bioassays Systems2008

    • Author(s)
      F.B. Fredj, M. Irie, J. Han, P. Yamada, A. Limam, A. Ghrabi H. Isoda
    • Organizer
      DT9
    • Place of Presentation
      Tunisia, Douz
    • Year and Date
      20081112-16
  • [Presentation] Contents of metal elements of Tunisian soils under olive cultivation in relation with total phenlic compounds of olive oil2008

    • Author(s)
      T. higashi, S. Sueya, M. Zarrouk, H. Suganuma H. Isoda
    • Organizer
      TJASSST
    • Place of Presentation
      Tunisia, Sousse
    • Year and Date
      20081109-11
  • [Presentation] Mineralogical and spectroscopic Investigations of limestone from Abiod formation2008

    • Author(s)
      A. Sdiri, T. Higashi, T. Hatta, F. Jamoussi, N. Tase H. Isoda
    • Organizer
      Tunisia13th Conference of the Geological Society of Africa
    • Place of Presentation
      Tunisia, Hammamet
    • Year and Date
      20081104-06
  • [Presentation] Environmental risk assessment of Tunisian water resoures using bioassays systems2008

    • Author(s)
      F.B. Fredj, M. Irie, J. Han, A,Limam, T.P.N. Talorete, A. Ghrabi, H. Isoda
    • Organizer
      日本沙漠学会第19回学術大会
    • Place of Presentation
      岡山
    • Year and Date
      20080524-25
  • [Presentation] Cistanche tubulosa(管花地精) 由来Acteosideのサイトカイン生産に及ぼす影響2008

    • Author(s)
      飯島理恵子、山田パリーダ、根本真衣、繁森英幸、礒田博子
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋
    • Year and Date
      20080326-29
  • [Presentation] Cistanche Tubulosa(管花地精) 由来抗酸化物質の抗アレルギー活性及びその作用メカニズム2007

    • Author(s)
      飯島理恵子、山田パリーダ、根本真衣、繁森英幸、礒田博子
    • Organizer
      JAACT
    • Place of Presentation
      高崎
    • Year and Date
      20070703-04
  • [Presentation] チュニジア原産オリーブオイルの好塩基球細胞における化学伝達物質及びサイトカイン遊離阻害効果2007

    • Author(s)
      山田パリーダ、モクタル・ザルック、川崎一則、礒田博子
    • Organizer
      日本沙漠学会第18回学術大会
    • Place of Presentation
      東京
    • Year and Date
      20070519-20
  • [Presentation] Leaf Extracts from Tunisian Oleave Cultivars Induce Growth Inhibition and Differentiation of Human Leukemia HL-60 Cells2006

    • Author(s)
      L.Abaza, T. P. N. Talorete, P. Yamada, M. Zarrouk, H. Isoda
    • Organizer
      JAACT
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-09-28
  • [Remarks] IDとパスワードを取得したい方は下記メールアドレスあるいは電話番号に御連絡願います。筑波大学北アフリカ研究センター 川田清和 Tel: 029-853-6599 kawada.arena@gmail.com

    • URL

      http://db.arena.tsukuba.ac.jp/arena/logon.do

  • [Patent(Industrial Property Rights)] 神経細胞保護剤、及びこれを含有する医薬品組成物、化粧料組成物並びに食品2006

    • Inventor(s)
      礒田博子、 ハンジュンキュ、他
    • Industrial Property Rights Holder
      筑波大学
    • Industrial Property Number
      特許, 特願2006-353103
    • Filing Date
      2006-12-27
  • [Patent(Industrial Property Rights)] フルボ酸を用いるI型アレルギー抑制剤及びI型アレルギーの発症抑制方法2006

    • Inventor(s)
      礒田博子、山田パリーダ、安部征雄
    • Industrial Property Rights Holder
      筑波大学
    • Industrial Property Number
      特許PCT/2006/300026
    • Filing Date
      2006-01-06
    • Overseas
  • [Patent(Industrial Property Rights)] 白血病予防用又は治療用の薬剤、並びに飲食物2006

    • Inventor(s)
      礒田博子、他
    • Industrial Property Rights Holder
      筑波大学・チュニジア高等教育省
    • Industrial Property Number
      特許, 特願2006-108549
    • Filing Date
      2006-04-11
  • [Patent(Industrial Property Rights)] メラニン産生抑制剤、及びこれを含有する美白用の医薬品組成物、化粧料組成物、並びに食品2006

    • Inventor(s)
      礒田博子、川野光子、森尾貴広
    • Industrial Property Rights Holder
      筑波大学
    • Industrial Property Number
      特許, 特願2006-353129
    • Filing Date
      2006-12-27
  • [Patent(Industrial Property Rights)] ツツジ科エリカ属由来成分を少なくとも含有する発毛用組成物、並びに該組成物を含有する医薬品、飲食物、及び化粧品2006

    • Inventor(s)
      礒田博子、川野光子、土田衛
    • Industrial Property Rights Holder
      筑波大学
    • Industrial Property Number
      特許, 特願2006-353214
    • Filing Date
      2006-12-27
  • [Patent(Industrial Property Rights)] アルツハイマー病予防又は治療剤、並びに飲食物2006

    • Inventor(s)
      礒田博子、繁森英幸、他
    • Industrial Property Rights Holder
      筑波大学
    • Industrial Property Number
      特許, 特願2006-29255
    • Filing Date
      2006-02-07

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Published: 2010-06-10   Modified: 2016-04-21  

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