Canine Behavior Genetics

2008 Fiscal Year Final Research Report

• Project/Area Number: 17380167
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Applied animal science
• Research Institution: The University of Tokyo
• Principal Investigator: TAKEUCHI Yukari The University of Tokyo, 大学院・農学生命科学研究科, 准教授 (10240730)
• Co-Investigator(Kenkyū-buntansha): MORI Yuji 東京大学, 大学院・農学生命科学研究科, 教授 (40157871) ; KIKUSUI Takefumi 東京大学, 大学院・農学生命科学研究科, 助手 (90302596)
• Project Period (FY): 2005 – 2008
• Keywords: 犬 / 気質 / 神経伝達物質 / 気質関連遺伝子 / 遺伝子多型 / 一塩基置換 / 盲導犬・探知犬 / 行動特性

Research Abstract

In order to investigate genetic background of temperamental individuality in dogs, we analyzed the relationship between the temperamental scores evaluated by the owners of Shiba Inu, and those by the trainers of guide dogs for blinds (Labrador Retriever) to polymorphisms of temperament-related genes. As the results, "aggression toward strangers", an important aspect of temperament, was related to a SNP on solute carrier family 1, member 2 gene in Shiba Inu and "activity" was related to the same SNP and a SNP on catecholamine-O-methyltransferase gene in Labrador Retrievers.

Research Products

• [Journal Article] An approach to canine behavioural genetics employing guide dogs for the blind. (2009)
  • Author(s): 武内ゆかり, Hashizume C., Arata S., Inoue-Murayama M., Maki T., Hart B.L., 森裕司
  • Journal Title: Anim Genet 40 Pages: 217-224
  • Peer Reviewed
• [Journal Article] Association analysis between canine behavioural traits and genetic polymorphisms in the Shiba Inu breed. (2009)
  • Author(s): 武内ゆかり, Kaneko F., Hashizume C., Masuda K., Ogata N., Maki T., Inoue-Murayama M., Hart B.L., 森裕司
  • Journal Title: Anim Genet 40 Pages: 616-622
  • Peer Reviewed
• [Journal Article] Sequences of canine glutamate decarboxylase (GAD) 1 and GAD2 genes, and variation of their genetic polymorphisms among five dog breeds. (2008)
  • Author(s): Arata S., Hashizume C., Kikusui T., 武内ゆかり, 森裕司
  • Journal Title: J Vet Med Sci 70 Pages: 1107-1110
  • Peer Reviewed
• [Journal Article] Sequences and polymorphisms of the canine monoamine transporter genes SLC6A2, SLC6A3, and SLC6A4 among five dog breeds. (2008)
  • Author(s): Arata S., Ogata N., Shimozuru M., 武内ゆかり, 森裕司
  • Journal Title: J Vet Med Sci 70 Pages: 917-975
  • Peer Reviewed
• [Journal Article] Identifying novel polymorphisms in the canine tryptophan hydroxylase 2 gene. (2008)
  • Author(s): Kaneko F., Masuda K., 武内ゆかり, 森裕司
  • Journal Title: J Vet Med Sci 70 Pages: 1117-1120
  • Peer Reviewed
• [Journal Article] 身近な動物から学ぶ気質の遺伝的背景 (2007)
  • Author(s): 武内ゆかり, 森裕司
  • Journal Title: 遺伝 61 Pages: 82-89
• [Journal Article] Polymorphisms in the canine glutamate transporter-1 gene : identification and variation among five dog breeds. (2006)
  • Author(s): Ogata N., Hashizume C., Momozawa Y., Masuda K., Kikusui T., 武内ゆかり, 森裕司
  • Journal Title: J Vet Med Sci 68 Pages: 157-159
  • Peer Reviewed
• [Journal Article] A comparison of the behavioral profiles of purebred dogs in Japan to profiles of those in the United States and the United Kingdom. (2006)
  • Author(s): 武内ゆかり, 森裕司
  • Journal Title: J Vet Med Sci 68 Pages: 789-796
  • Peer Reviewed
• [Journal Article] Identification of an cysteine-to-arginine substitution caused by a single nucleotide polymorphism in the canine monoamine oxidase B gene. (2005)
  • Author(s): Hashizume C., Masuda K., Momozawa Y., Kikusui T., 武内ゆかり, 森裕司
  • Journal Title: J Vet Med Sci 67 Pages: 199-201
  • Peer Reviewed
• [Journal Article] Canine tyrosine hydroxylase (TH) gene and dopamine beta-hydroxylase (DBH) gene : their sequences, genetic polymorphisms, and diversities among five different dog breeds. (2005)
  • Author(s): 武内ゆかり, Hashizume C., Chon E.M., Momozawa Y., Masuda K., Kikusui T., 森裕司
  • Journal Title: J Vet Med Sci 67 Pages: 861-867
  • Peer Reviewed
• [Presentation] Assessing canine temperament related to aggression. (2009)
  • Author(s): Kaneko F., Momozawa Y., Takeuchi Y., Mori Y.
  • Organizer: 7th International Veterinary Behaviour Meeting
  • Place of Presentation: Edunburgh, UK.
  • Year and Date: 2009-10-29
• [Presentation] Predicting the outcome of detector dog training based on their behavior and genetic characteristics. (2007)
  • Author(s): Ogata N., Vandeloo J., Kikusui T.,Takeuchi Y., Mori Y.
  • Organizer: 6th International Veterinary Behavior Meeting (IVBM)
  • Place of Presentation: Riccione, Italy.
  • Year and Date: 2007-06-18
• [Presentation] Search for temperament-associated genes in guide dogs. (2007)
  • Author(s): Arata S., Kaneko F., Momozawa Y., Ogata N., Yoshizawa S., Fukui R., Tawada S., Nakamura T., Kikusui T., Takeuchi Y., Mori Y.
  • Organizer: 6th International Veterinary Behavior Meeting (IVBM)
  • Place of Presentation: Riccione, Italy.
  • Year and Date: 2007-06-17
• [Presentation] Behavioral Genetics and Its Application to Veterinary Clinics. (2005)
  • Author(s): Takeuchi Y.
  • Organizer: 142nd AVMA Annual Convention
  • Place of Presentation: Minneapolis, U.S.A.
  • Year and Date: 2005-07-18
• [Book] 「ヒトと動物の関係学」第3巻ペツトと社会(破綻する生活-ペットの問題行動と飼い主)(林良博他編) (2008)
  • Author(s): 武内ゆかり(分担)
  • Total Pages: 155-178
  • Publisher: 岩波書店
• [Book] はじめてでも失敗しない愛犬の選び方 (2007)
  • Author(s): 武内ゆかり
  • Total Pages: 191
  • Publisher: 幻冬舍
• [Remarks] 武内ゆかり(監訳)2009動物病院における獣医動物行動学の適用と展望インターズー
• [Remarks] 武内ゆかり(監修)2006図解雑学Q&Aイヌの本音ナツメ社
• [Remarks] 武内ゆかり(監訳), 尾形庭子, 加隈良枝, 橋爪知恵(分担訳)2005臨床獣医行動学の最新情報学窓社
• [Remarks] ホームページ等
  • URL: http://www.vm.a.u-tokyo.ac.jp/koudou/j-research2.htm