2018 Fiscal Year Annual Research Report
Paradox of relationship between social gradients and noncommunicable disease in develop ing countries.
| Project/Area Number |
17F17110
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
中村 桂子 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (00211433)
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| Co-Investigator(Kenkyū-buntansha) |
RAHMAN MD. Mosiur 東京医科歯科大学, 医歯(薬)学総合研究科, 外国人特別研究員
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| Project Period (FY) |
2017-10-13 – 2020-03-31
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| Keywords | Diabetes / Glycemic level / diet / medication / physical exercise / health-related QOL / Bangladesh |
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| Outline of Annual Research Achievements |
To identify the factors associated with barriers to and determinants of poor glycemic control, we have planned to conduct a cohort study in 500 type 2 diabetics aged 21 years and over from three diabetics center, located in three divisional cities in Bangladesh. We analyzed the baseline data of this cohort study. The results of the baseline data indicate that, from the total sample population, 50.2% were male, 33.8% were 21-46 years old, 14.6% had no education, and 80.0% were living in a nuclear family. Approximately 37.0% were living in rural areas and 33.0% were defined as being rich. The results of the analyses indicated that 57.4% of the study participants were not adhering to recommended oral hypoglycemic agents, only 26.0% of reported adhering to dietary recommendations, and adherence to prescribed recommendations for physical activity were 37.8%. Approximately 62.0% of patients reported not performing self-monitoring of blood glucose. A substantial percentage (71.8%) of the patients had poor blood glycemic control (HbA1c<7.0%) and 33.2% of them visited the diabetics center regularly. The result also shows that more than two-fifths of the patients (41.0%) were either overweight or obese. Approximately 44.0% of patients were suffering from hypertension and 42.6% reported to suffer from depression.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
Our research has progressed smoothly. During this period from April 2018-March 2019, we developed our study protocol (developed the questionnaires, reviewed the instruments for collection of data, estimated the budget, and the number of interviewers required for our data collection, and submitted our ethical documents to TMDU IRB and Ethical Committee of the Institute of Biological Sciences, University of Rajshahi, Bangladesh). After receiving the ethical approval, we have already collected our baseline data between the period from July 2018 to September 2018. We are now in a stage to analyze the baseline data. Using the baseline data, we already finished the analyses of six of our tentative manuscripts under the following headings: 1) Mediators of the association between low socioeconomic status and poor glycemic control among type 2 diabetic in Bangladesh; 2) Relative contribution of selected risk factors to prevalence and severity of periodontal disease in patients with diabetics in Bangladesh; 3) Identifying perceived barriers to recommended diet, medication, and physical activity adherence in type 2 diabetics: an exploratory factorial analysis; 4) Association of good glycemic control and cost of diabetes care in Bangladesh; 5) The role of perceived barriers in explaining socio-economic status differences in adherence to diet, medication and physical activity guidelines in type 2 diabetics: a mediation study; 6) Assessment of the quality of life through the SF-12 questionnaire in diabetic patients according to prevalence and severity of periodontal disease.
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| Strategy for Future Research Activity |
1. Conduct end line survey
2. Finalize the manuscript (using the baseline data) for submission to international journals
3. Entry end line data and perform analysis
4. Writing the manuscript using the cohort study data and submit the manuscript to journals
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