2009 Fiscal Year Final Research Report
Regulation mechanism of biomineralization based on interaction between organic matrices and inorganic crystals
| Project/Area Number |
17GS0311
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| Research Category |
Grant-in-Aid for Creative Scientific Research
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| Allocation Type | Single-year Grants |
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| Research Institution | The University of Tokyo |
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Principal Investigator |
NAGASAWA Hiromichi The University of Tokyo, 大学院・農学生命科学研究科, 教授 (60134508)
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| Co-Investigator(Kenkyū-buntansha) |
KOGURE Toshihiro 東京大学, 大学院・理学系研究科, 准教授 (50282728)
TAKAGI Yasuaki 北海道大学, 大学院・水産科学研究院, 教授 (10212002)
SAKUDA Shohei 東京大学, 大学院・農学生命科学研究科, 准教授 (80192087)
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| Project Period (FY) |
2005 – 2009
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| Keywords | バイオミネラリゼーション / 石灰化 / 水棲生物 / 有機・無機相互作用 / 有機基質 / 結晶多形制御 / 結晶成長制御 / 分子進化 |
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| Research Abstract |
It has been hypothesized that biomineralization, an action of mineral formation by organisms, is regulated by a small amount of organic materials included in biominerals. Using calcified tissues of some aquatic organisms we searched for calcification-regulating organic compounds, and purified them for structural and functional identification. We also clarified the crystallographic properties of each calcified tissue by electron microscopic analyses and verified the hypothesis by discovering many high- and low-molecular-weight organic compounds, which regulate calcification.
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[Presentation] Structural and functional analyses of a novel matrix protein, Pif, from the nacreous layer of the Japanese pearl oyster, Pinctada fucata2008
Author(s)
鈴木道生, 猿渡和子, 山本祐也, 西村達也, 加藤隆史, 小暮敏博, 長澤寛道
Organizer
Gordon Research Conference, Biomineralization
Place of Presentation
New Hampshire, USA.
Year and Date
20080810-20080815
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