2021 Fiscal Year Final Research Report
Mid-infrared pulse generation and shaping in engineered quasi-phase-matched nonlinear crystals for protein dynamics control
| Project/Area Number |
17K05077
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Optical engineering, Photon science
|
|---|
| Research Institution | Saitama University (2019-2021)
Osaka University (2017-2018) |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
神村 共住 大阪工業大学, 工学部, 教授 (40353338)
梅村 信弘 公立千歳科学技術大学, 理工学部, 准教授 (40580098)
|
|---|
| Project Period (FY) |
2017-04-01 – 2022-03-31
|
| Keywords | 赤外レーザ / 準周期疑似位相整合 |
|---|
| Outline of Final Research Achievements |
In this study, we investigate engineered quasi-phase-matching structures that can simultaneously realize differential frequency mixing and pulse shaping in the mid-infrared region for artificially controlling structural transitions in proteins. Numerical simulations were performed on a typical crystal, LiNbO3, and quasi-phase-matching structures for narrow-band pulses, chirped pulses, pulse trains, and multiple-wavelength pulses, which are important optical pulse shapes in vibration control of molecules and proteins, were demonstrated. We also constructed a mid-infrared multi-pulse spectroscopy system for control of protein dynamics.
|
| Free Research Field |
光物性物理
|
| Academic Significance and Societal Importance of the Research Achievements |
中赤外領域にはタンパク質の構造や機能において重要な役割を果たす振動モードが多数存在する。それらのエネルギーに共鳴する中赤外光を照射することによって、人為的に構造変化や機能発現・抑止ができれば、生命科学分野の研究開発が大きく加速する。そのためには中赤外光の波形制御技術が重要となる。可視域では確立している光波形制御技術であるが、中赤外領域ではまだ未成熟である。本研究は、中赤外光の波形制御手法の新しい提案である。
|
