2018 Fiscal Year Final Research Report

Estimated numbers of patients with duplicate diseases of liver disease related to hepatitis B or C virus infection based on reconstructed from medical claims

Research Project

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Project/Area Number	17K19817
Research Category	Grant-in-Aid for Challenging Research (Exploratory)
Allocation Type	Multi-year Fund
Research Field	Society medicine, Nursing, and related fields
Research Institution	Hiroshima University
Principal Investigator	Ohisa Masayuki 広島大学, 医系科学研究科(医), 助教 (20727250)
Co-Investigator(Kenkyū-buntansha)	杉山文広島大学, 医歯薬保健学研究科(医), 助教 (50778280) 田中純子広島大学, 医歯薬保健学研究科(医), 教授 (70155266)
Project Period (FY)	2017-06-30 – 2019-03-31
Keywords	肝炎ウイルス / B型肝炎 / C型肝炎 / 重複疾患 / 患者数推計 / 診療報酬記録 / レセプト
Outline of Final Research Achievements	In order to clarify the distribution and frequency of duplicate diseases of liver disease-related patients derived from hepatitis virus, we analyzed 77, 773, 235 medical claims of 3,462,296 people belonging to the Health Insurance Society in 2014-2016. The three-year period prevalence during 2014-2016 was 100,000 versus pairs 200.8 for hepatitis B-related disease and 170.6 for hepatitis C-related disease. The percentage of patients with hepatitis B / C-related disease at age 0-64 who had consulted a medical institution had duplicate diseases was 83.1% respectively.Duplicated Diseases frequently are gastritis, duodenitis, lipid abnormalities, rhinitis, hypertension and the like, and it was clarified that many diseases fall under internal medicine (chronic diseases), otology and medicine (acute diseases).
Free Research Field	数理疫学
Academic Significance and Societal Importance of the Research Achievements	肝炎ウイルスの持続感染は肝硬変、肝癌のハイリスク因子である。肝炎は自覚症状が現れにくく、潜在しているキャリア、患者としてすでに治療・入院しているキャリア、（継続的な）受診しないままであるキャリアの社会存在状態別に対策を立てる事が重要である。キャリアとして掘り起こされたとしても、肝臓内科にかからないキャリアや、他の診療科で見出されたキャリアが肝臓内科に受診されない可能性がある。本解析による重複疾患の頻度・分布のデータはキャリアの掘り起こしのための基礎資料となる。