Studies on pathogen recognition and functional expression for plant immunity mediated by ubiquitin modification

2021 Fiscal Year Final Research Report

• Project/Area Number: 18H02162
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Review Section: Basic Section 38060:Applied molecular and cellular biology-related
• Research Institution: Hokkaido University
• Principal Investigator: Yamaguchi Junji 北海道大学, 理学研究院, 教授 (10183120)
• Co-Investigator(Kenkyū-buntansha): 佐藤 長緒 北海道大学, 理学研究院, 准教授 (50609724)
• Project Period (FY): 2018-04-01 – 2021-03-31
• Keywords: ユビキチンリガーゼ / 植物免疫 / 病原体認識受容体

Outline of Final Research Achievements

In this study, we focused on the function of ATL31, a membrane-localized ubiquitin ligase conserved in plants, and investigated the signal transduction mechanism regulating pathogen resistance in plants. Our biochemical analyzes demonstrated that ATL31’s ubiquitin ligase activity was changed in response to MAMPs. We also found the specific ubiquitin chain type signals are involved in the ATL31-mediating pathogen attack signals in plan cells.

Free Research Field

農学

Academic Significance and Societal Importance of the Research Achievements

植物の病原体抵抗性（植物免疫）は，農作物の収量向上を実現する上で重要な植物生理現象である。本研究で，これまで分かっていなかった植物免疫におけるユビキチンシグナルの関与が示された。本研究成果は，植物免疫を制御する分子基盤の理解や複数の環境ストレスに対する植物の適応機構の解明に貢献すると期待される。