2009 Fiscal Year Final Research Report
Novel Reaction Using Active Species Derived from Imidazolium Salts
| Project/Area Number |
19390001
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Hokkaido University |
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Principal Investigator |
SATO Yoshihiro Hokkaido University, 大学院・薬学研究院, 教授 (90226019)
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| Research Collaborator |
OONISHI Yoshihiro 北海道大学, 大学院・薬学研究院, 助教 (70399955)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 遷移金属錯体 / 含窒素ヘテロ環カルベン / イオン液体 / 環境調和型反応 |
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| Research Abstract |
The objective of this research is comprehensive understanding of the chemistry of N-heterocyclic carbenes (NHCs) and that of ionic liquids (ILs), those have recently received much attention but have been independently studied. During the term of this research project, we have succeeded in finding a novel catalytic asymmetric three-component coupling reaction of 1,3-diene, aldehyde, and silanes using a chiral NHC nickel complex. And, we have also established two Rh-catalyzed cyclizations, in which catalyst can be recycled in several times, by using IL as a reaction medium.
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