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2009 Fiscal Year Final Research Report

Reorganization of brain motor network after stroke visualized with fMRI and tractography

Research Project

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Project/Area Number 19500458
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionInternational University of Health and Welfare

Principal Investigator

KATO Hiroyuki  International University of Health and Welfare, 大学病院, 教授 (60224531)

Co-Investigator(Kenkyū-buntansha) HASHIMOTO Ritsuo  国際医療福祉大学, 大学病院, 教授 (50254917)
HIWATARI Masao  国際医療福祉大学, 大学院, 教授 (20189898)
Project Period (FY) 2007 – 2009
Keywords脳神経疾患 / リハビリテーション / 脳卒中 / 脳機能画像診断
Research Abstract

We performed both fMRI and diffusion tensor tractography in stroke patients in an attempt to elucidate the mechanism of motor recovery after stroke. The observed change in the brain motor network after stroke was a dynamic process including (1) functional recovery from reversible damage and (2) compensation, recruitment, and reorganization of brain motor network, depending on the damage to the pyramidal tract. This change was observed within the first 2 months after stroke, suggesting the existence of a critical period.

  • Research Products

    (21 results)

All 2009 2008 2007

All Journal Article (10 results) (of which Peer Reviewed: 5 results) Presentation (10 results) Book (1 results)

  • [Journal Article] Reaction time differences between left-and right handers during mental rotation of hand pictures2009

    • Author(s)
      Takeda K, Shimoda N, Sato Y, Ogano M, Kato H
    • Journal Title

      Laterality (in press)

    • Peer Reviewed
  • [Journal Article] 画像で見る脳の再構築2009

    • Author(s)
      加藤宏之、武田湖太郎
    • Journal Title

      37(8)

      Pages: 699-704

  • [Journal Article] NIRSを用いた脳機能評価2009

    • Author(s)
      武田湖太郎、加藤宏之
    • Journal Title

      Clinical Neuroscience 27

      Pages: 1055-1057

  • [Journal Article] 随意運動の機能回復:機能的MRIの知見2009

    • Author(s)
      加藤宏之
    • Journal Title

      Jpn J Rehabil Med 46(1)

      Pages: 17-21

  • [Journal Article] Sensorimotor cortex activation during mirror therapy in healthy right-handed subjects: a study with near-infrared spectroscopy2008

    • Author(s)
      Imai I, Takeda K, Shiomi T, Tanuguchi T, Kato H
    • Journal Title

      J Phys Ther Sci 20

      Pages: 141-145

    • Peer Reviewed
  • [Journal Article] Cerebral laterality differences in handedness: a mental rotation study with NIRS2008

    • Author(s)
      Shimoda N, Takeda K, Imai I, Kaneko J, Kato H
    • Journal Title

      Neurosci Lett 430(1)

      Pages: 43-7

    • Peer Reviewed
  • [Journal Article] 近赤外光トポグラフィーによる運動機能の評価2008

    • Author(s)
      武田湖太郎、加藤宏之、渡辺英寿
    • Journal Title

      臨床脳波 50

      Pages: 397-404

  • [Journal Article] Shift of motor activation areas during recovery from hemiparesis after cerebral infarction: a longitudinal study with near-infrared spectroscopy2007

    • Author(s)
      Takeda K, Gomi Y, Imai I, Shimoda N, Hiwatari M, Kato H
    • Journal Title

      Neurosci Res 59(2)

      Pages: 136-44

    • Peer Reviewed
  • [Journal Article] 脳機能再構築に関する脳機能画像診断の実際2007

    • Author(s)
      加藤宏之
    • Journal Title

      理学療法科学 22

      Pages: 7-12

  • [Journal Article] 慢性期脳卒中患者の麻痺手運動時における同側大脳半球の活性化-近赤外分光法による検討-2007

    • Author(s)
      武田湖太郎、五味幸寛、今井樹、下田信明、加藤宏之
    • Journal Title

      脳科学とリハ 7

      Pages: 15-20

    • Peer Reviewed
  • [Presentation] False positive/negative hemoglobin signal of near-infrared specteoscopy2009

    • Author(s)
      Takeda K, Osu R, Otaka Y, Kato H
    • Organizer
      Neuroscience 2009
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-21
  • [Presentation] Motor imagery in mental rotation of hands in left- and right-handers: A behavioral and near-infrared spectroscopy study2009

    • Author(s)
      Shimoda N, Takeda K, Kato H
    • Organizer
      Neuroscience 2009
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-19
  • [Presentation] NIRSを用いた脳卒中後の片麻痺の回復と脳機能再構築の検討.2009

    • Author(s)
      加藤宏之、武田湖太郎、橋本律夫、下田信明、今井樹
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2009-05-20
  • [Presentation] Longitudinal NIRS study on motor-functional recovery after hemiparetic stroke2008

    • Author(s)
      Takeda K, Imai I, Shimoda N, Kato H
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-11-17
  • [Presentation] シンポジウム:ニューロリハビリテーションへの臨床神経生理学の応用-脳卒中などへの応用を中心に-、「脳機能再構築に関する脳機能画像診断」2008

    • Author(s)
      加藤宏之
    • Organizer
      第38回日本臨床神経生理学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-12
  • [Presentation] 頭部傾斜がNIRSデータへ与える影響:擬陽性の評価2008

    • Author(s)
      武田湖太郎、郡司幸也、渡邉観世子、加藤宏之
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-09
  • [Presentation] シンポジウム.脳の機能再編成:機能画像の知見から.「随意運動の機能回復;機能的MRIの知見」2008

    • Author(s)
      加藤宏之
    • Organizer
      第45回日本リハビリテーション医学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2008-06-04
  • [Presentation] Comparative study of motor related activation areas after hemiparetic stroke between well- and poorly recovered patients using near-infrared spectroscopy2007

    • Author(s)
      Takeda K, Gomi Y, Imai I, Shimoda N, Hiwatari M, Kato H
    • Organizer
      Neuroscience 2007
    • Place of Presentation
      San Diego, USA
    • Year and Date
      20071103-20071107
  • [Presentation] Local cerebral hemodynamic response in frontal and parietal cortices during mental rotation of hand: a near-infrared spectroscopy study2007

    • Author(s)
      Shimoda N, Takeda K, Imai I, Kaneko J, Taniguchi T, Kato H
    • Organizer
      Neuroscience 2007
    • Place of Presentation
      San Diego, USA
    • Year and Date
      20071103-20071107
  • [Presentation] Transient hyperactivation in bilateral motor related areas during recovery from poststroke mild hemiparesis - a study with NIRS -2007

    • Author(s)
      Takeda T, Imai I, Maruyama K, Gomi Y, Shimoda N, Hiwatari M, Kato H
    • Organizer
      23rd International Symposium on Cerebral Blood Flow, Metabolism & Function
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      20070520-20070524
  • [Book] 脳卒中に対する標準的理学療法介入(潮見泰蔵、編, 脳卒中になったら、まず何が行われるの?. 脳卒中の標準治療)2007

    • Author(s)
      加藤宏之
    • Total Pages
      11-23
    • Publisher
      文光堂

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Published: 2011-06-18   Modified: 2016-04-21  

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