2009 Fiscal Year Final Research Report
Basic study that examining immune regulatory effect of soy isoflavones.
| Project/Area Number |
19500685
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | The University of Tokushima |
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Principal Investigator |
SAKAI Tohru The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 教授 (40274196)
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| Project Period (FY) |
2007 – 2009
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| Keywords | イソフラボン / 免疫 / 大腸炎 |
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| Research Abstract |
Soy foods have been consumed for centuries in Asian countries. Human clinical and epidemiological studies have revealed many potential benefits of intake of soy products. In this study, we therefore investigated the effects of equol on ovalbumin (OVA)-speficic T cell and B cell responses in BALB/c mice. Mice that had been treated with 20mg/kg equol showed a significantly higher level of OVA-specifc IgE than that in control mice. Furthermore, equol perpetrated DSS-induced colitis in BALB/c mice.
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