2009 Fiscal Year Final Research Report
Synthesis of Propellane-Type Heterocycles Using Tandem Cyclization
| Project/Area Number |
19550046
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Organic chemistry
|
|---|
| Research Institution | Kumamoto University |
|---|
Principal Investigator |
NISHINO Hiroshi Kumamoto University, 大学院・自然科学研究科, 教授 (50145281)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Keywords | タンデム環化反応 / 複素環プロペラン類 / 酸化反応 / ラジカル反応 / プロペラ型化合物 / ビシクロ化合物 / Lewis酸 / 分子内環化反応 |
|---|
| Research Abstract |
Tandem cyclization is a successive intramolecular cyclization when the cyclization is once started, and important for the synthesis of organic cyclization compounds as an efficient synthetic technique. In the research project, the synthesis of novel propellane-type heterocyclic compounds and cyclophane-type macrolides using manganese (III) acetate-based oxidative radical tandem cyclization was studied. The biological activities and physicochemical interests of these compounds are expected.
|
