2009 Fiscal Year Final Research Report
Analysis of physiological functions of the fission yeast ammonium transporters
| Project/Area Number |
19570138
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional biochemistry
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| Research Institution | Nihon University Junior College |
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Principal Investigator |
MITSUZAWA Hiroshi Nihon University Junior College, 短期大学部・生物資源学科, 准教授 (50202346)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 膜輸送と輸送タンパク質 |
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| Research Abstract |
In microorganisms and plants, ammonium is an important nitrogen source that is used for amino acid synthesis. Microorganisms and plants have mechanisms of its uptake. In this study, fission yeast was used as a model to elucidate physiological functions of ammonium transporter, which mediate transport of ammonium across the membrane. It has been found that ammonium transporter plays a role not only in uptake of ammonium from the environment but also in morphological differentiation from yeast to filamentous form induced by low ammonium and retention of intracellular ammonium produced from metabolism.
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