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2009 Fiscal Year Final Research Report

Chemical Biology of Golgi Membrane Dynamics

Research Project

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Project/Area Number 19580098
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied microbiology
Research InstitutionHosei University

Principal Investigator

TAKATSUKI Akira  Hosei University, 生命科学部, 教授 (80011972)

Project Period (FY) 2007 – 2009
Keywordsゴルジ / 抗生物質 / ケミカルバイオロジー / 中心体 / 微小管 / 膜ダイナミクス
Research Abstract

The Golgi maintains its characteristic structure by a dynamic equilibrium manner, but this mechanism remains to be clarified. Chemicals affecting Golgi membrane dynamics were found at a relatively high ratio among those known to affect transition to mitotic phase of cell cycle and induce apoptosis. Results indicating that they act on the centrosome suggest that the centrosome plays important roles in the control of Golgi membrane dynamics.

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Published: 2011-06-18   Modified: 2016-04-21  

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