Associations of Psychological Factors with Inflammation, Metabolic Disorder, and Autonomic Function

2009 Fiscal Year Final Research Report

• Project/Area Number: 19590629
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Osaka University
• Principal Investigator: OHIRA Tetsuya Osaka University, 医学系研究科, 准教授 (50448031)
• Co-Investigator(Kenkyū-buntansha): ISO Hiroyasu 大阪大学, 医学系研究科, 教授 (50223053) ; TANIGAWA Takeshi 愛媛大学, 医学系研究科, 教授 (80227214) ; IMANO Hironori 大阪大学, 医学系研究科, 助教 (90450923)
• Project Period (FY): 2007 – 2009
• Keywords: 成人保健 / ストレス / うつ / 炎症 / 代謝異常 / 自律神経

Research Abstract

We sought o examine associations of psychological factors with life style, inflammation, metabolic syndrome, and autonomic function among Japanese men and women. In a 3-year prospective analysis, perceive stress, physical activity, over working time, and insufficient sleep were associated with the risk of depressive symptoms. In a cross-sectional analysis, stressful life event, anger, chronic fatigue, and hopelessness were associated with high sensitive C reactive protein levels, prevalence of metabolic syndrome, and increased sympathetic functions.

Research Products

• [Journal Article] Associations of psychological distress with cardiovascular disease and its risk factors: the Circulatory Risk in Communities Study(CIRCS) (2010)
  • Author(s): Ohira T.
  • Journal Title: Journal of Epidemiology 20 Pages: 185-191
  • Peer Reviewed
• [Journal Article] Perceived level of life enjoyment and risks of cardiovascular disease incidence and mortality: The JPHC Study. Circuletion (2009)
  • Author(s): Shirai K, Iso H, Ohira T, Ikeda A, Noda H, Honjo K, Inoue M, Tsugane S
  • Journal Title: Japan Public Health Center-Based Study Group 120 Pages: 956-963
  • Peer Reviewed
• [Journal Article] Effects of habitual alcohol intake on ambulatory blood pressure, heart rate, and its variability among Japanese men (2009)
  • Author(s): Ohira T, Tanigawa T, Tabata M, Imano H, Kitamura A, Kiyama M, Sato S, Okamura T, Cui R, Koike KA, Shimamoto T, Iso H.
  • Journal Title: Hypertension 53 Pages: 13-19
  • Peer Reviewed
• [Journal Article] The joint impact of self-reported behaviors of eating quickly and eating until full on overweight: results of a cross sectional survey (2008)
  • Author(s): aruyama K, Sato S, Ohira T, Maeda K, Noda H, Kubota Y, Nishimura S, Kitamura A, Kiyama M, Okada T, Imano H, Nakamura M, Ishikawa Y, Kurokawa M, Sasaki S, Iso H. The joint impact of self-report
  • Journal Title: BMJ 337 Pages: a2002
  • Peer Reviewed
• [Journal Article] メタボリックシンドロームの心血管リスク虚血性心疾患vs脳卒中 (2008)
  • Author(s): 大平哲也, 磯博康
  • Journal Title: ebmジャーナル 9 Pages: 14-18
• [Journal Article] 本邦脂質異常症の現況と脳卒中発症-疫学的検討の変遷- (2008)
  • Author(s): 大平哲也, 磯博康
  • Journal Title: 生活習慣病と成人病 38 Pages: 134-138
• [Journal Article] メタボリックシンドローム構成因子に及ぼす肥満と生活習慣の影響についての縦断研究 (2008)
  • Author(s): 木山昌彦, 大平哲也, 北村明彦, 今野弘規, 岡田武夫, 佐藤眞一, 前田健次, 中村正和, 石川善紀, 嶋本喬, 野田博之, 磯博康
  • Journal Title: 厚生の指標 55 Pages: 1-5
  • Peer Reviewed
• [Journal Article] Associations of psychosocial factors with heart rate and its short-term variability: multi-ethnic study of atherosclerosis (2008)
  • Author(s): Ohira T, Diez Roux AV, Prineas RJ, Kizilbash MA, Carnethon MR, Folsom AR
  • Journal Title: Psychosomatic Medicine 70 Pages: 141-146
  • Peer Reviewed
• [Journal Article] Longitudinal association of serum carotenoids and tocopherols with hostility: the CARDIA study (2008)
  • Author(s): Ohira T, Hozawa A, Iribarren C, Daviglus ML, Matthews KA, Gross MD, Jacobs DR Jr
  • Journal Title: American Journal of Epidemiology 167 Pages: 42-50
  • Peer Reviewed
• [Journal Article] 心理的健康の維持・増進のための望ましい生活習慣についての疫学研究 (2007)
  • Author(s): 大平哲也, 中村知佳子, 今野弘規, 岡田武夫, 北村明彦, 木山昌彦, 中川裕子, 佐藤眞一, 中村正和, 内藤義彦, 黒川通典, 仲下祐美子, 山本雅代, 亀井和代, 堀井裕子, 嶋本喬
  • Journal Title: 日本公衆衛生雑誌 54 Pages: 226-235
  • Peer Reviewed
• [Presentation] "笑い"が将来の心身医学を変える!? (2010)
  • Author(s): 大平哲也
  • Organizer: 第49回日本心身医学会九州地方会教育講演
  • Place of Presentation: 宮崎
  • Year and Date: 2010-02-07
• [Presentation] 睡眠呼吸障害と家庭血圧・心電図との関連についての疫学研究 (2009)
  • Author(s): 大平哲也
  • Organizer: 第68回日本公衆衛生学会総会
  • Place of Presentation: 奈良
  • Year and Date: 2009-10-21
• [Presentation] 疲労とメタボリックシンドロームとの関連についての疫学研究 (2009)
  • Author(s): 大平哲也
  • Organizer: 第50回日本心身医学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-06-06
• [Presentation] 心理的因子と炎症との関連についての疫学研究 (2008)
  • Author(s): 大平哲也
  • Organizer: 第67回日本公衆衛生学会総会
  • Place of Presentation: 福岡
  • Year and Date: 2008-11-05
• [Presentation] Fatigue and metabolic syndrome among Japanese men and women (2008)
  • Author(s): Ohira T
  • Organizer: International Conference on Fatigue Science
  • Place of Presentation: 沖縄
  • Year and Date: 2008-09-04
• [Presentation] 笑いの頻度と認知機能の関連についての疫学研究 (2008)
  • Author(s): 大平哲也
  • Organizer: 第15回日本笑い学会総会
  • Place of Presentation: 京都
  • Year and Date: 2008-07-13
• [Presentation] 肩こり、腰痛と身体心理的因子・生活習慣との関連についての疫学研究 (2008)
  • Author(s): 大平哲也
  • Organizer: 第49回日本心身医学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-06-12
• [Presentation] 楽観的思考と循環器疾患危険因子との関連についての縦断研究 (2007)
  • Author(s): 大平哲也
  • Organizer: 第66回日本公衆衛生学会総会
  • Place of Presentation: 松山
  • Year and Date: 2007-10-25
• [Presentation] 笑いの頻度とメタボリックシンドローム構成因子との関連についての疫学研究 (2007)
  • Author(s): 大平哲也
  • Organizer: 第48回日本心身医学会総会
  • Place of Presentation: 福岡
  • Year and Date: 2007-05-25