2010 Fiscal Year Final Research Report
prospective study on the sensitivity and specificity of electrodiagnostic criteria of CIDP : the utility of SEPs
| Project/Area Number |
19591011
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neurology
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| Research Institution | Teikyo University |
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Principal Investigator |
SONOO Masahiro Teikyo University, 医学部, 教授 (40231386)
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| Co-Investigator(Kenkyū-buntansha) |
HATANAKA Yuki 帝京大学, 医学部, 助教 (40322458)
TSUKAMOTO Hiroshi 帝京大学, 医学部, 助手 (80459320)
KUROKAWA Katsumi 川崎医科大学, 医学部, 准教授 (20289177)
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| Project Period (FY) |
2007 – 2010
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| Keywords | CIDP / 体性感覚誘発電位 / 神経伝導検査 / 脛骨神経 / 神経根 |
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| Research Abstract |
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is one of intractable neurological diseases, and is usually diagnosed using nerve conduction studies (NCSs). However, a low diagnostic sensitivity has been a problem of the previous methods, which may be due to the fact that NCS cannot evaluate the proximal portion of the peripheral nerve that is preferentially involved in CIDP. The present study evaluated CIDP patients using tibial nerve somatosensory evoked potentials (SEPs), which documented proximal-dominant delay in most CIDP patients and achieved a higher diagnostic sensitivity than NCSs.
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