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2008 Fiscal Year Final Research Report

Reconstruction of lower urinary tract function by transplantation of bone marrow cells into the brain and spinal cord in rats with overactive bladder

Research Project

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Project/Area Number 19591861
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Urology
Research InstitutionUniversity of the Ryukyus

Principal Investigator

SUGAYA Kimio  University of the Ryukyus, 医学部, 准教授 (20179120)

Project Period (FY) 2007 – 2008
Keywords過活動膀胱 / 骨髄間質細胞 / 移植
Research Abstract

排尿障害を呈する脳梗塞ラットまたは脊髄損傷ラットの脳脊髄髄腔内へ骨髄間質細胞を移植し、下部尿路機能の再構築の可能性について検討した。その結果、ドナー由来の移植細胞は脳や脊髄に定着し、一部のラットでは移植由来細胞は神経様細胞に分化しており、排尿障害も部分的に改善された。

  • Research Products

    (1 results)

All 2007

All Journal Article (1 results) (of which Peer Reviewed: 1 results)

  • [Journal Article] Restoration of bladder contraction by bone marrow transplantation in rats with underactive bladder2007

    • Author(s)
      Nishijima S, Sugaya K, Miyazato M,Kadekawa K, Oshiro Y, Uchida A, Hokama S, Ogawa Y.
    • Journal Title

      Biomed Res 28

      Pages: 275-280

    • Peer Reviewed

URL: 

Published: 2010-06-10   Modified: 2016-04-21  

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