Estimation of the Stress under Personal Computer Work by Salivary Secretory Substances

2008 Fiscal Year Final Research Report

• Project/Area Number: 19700204
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Sensitivity informatics/Soft computing
• Research Institution: Nagaoka University of Technology (2008); Shimane University (2007)
• Principal Investigator: NOMURA Shusaku Nagaoka University of Technology, 産学融合トップランナー養成センター, 特任准教授 (80362911)
• Project Period (FY): 2007 – 2008
• Keywords: 感性生理 / 感性評価 / ストレス / 唾液 / 免疫 / ホルモン / 快・不快

Research Abstract

唾液中に分泌されるホルモンや免疫物質を、精神的ストレスの客観的評価指標(バイオマーカー)として利用することを目的とした。本研究では、パソコン作業による断続的な精神作業負荷に対する五種類のバイオマーカーを同時・経時的に評価したところ、(1)ストレス反応の時定数の差異に基づくと思われる各バイオマーカーの反応特性の相違を発見し、(2)さらに、それを参照することで、いわゆる精神ストレスの"蓄積"の生理的評価手法となり得ることを示した。

Research Products

• [Journal Article] 唾液中のコルチゾールによる軽度な精神作業負荷の生理評価 (2009)
  • Author(s): 野村収作, 水野統太, 野澤昭雄, 浅野裕俊, 井出英人
  • Journal Title: バイオフィードバック研究 36(1) Pages: pp.23-32
  • Peer Reviewed
• [Journal Article] Effect of the Relief from Chronic Stress during Graduation Examination on Salivary Biomarkers (2009)
  • Author(s): Shusaku Nomura, Hideki Ohira, and Tsutomu Kamei
  • Journal Title: Transactions of Japan Society of Kansei Engineering 8(3) Pages: pp.481-488
  • Peer Reviewed
• [Journal Article] An Application of Rough Set Analysis to a Psycho-Physiological Stress Research (2009)
  • Author(s): Shusaku Nomura, Santoso Handri, and Yasuo Kudo
  • Journal Title: in Proceedings of IADIS International Conference IADIS ICT, Society and Human Beings Pages: 8 pages, in press
  • Peer Reviewed
• [Journal Article] ストレスバイオマーカの現在:PNEI指標の測定と課題 (2009)
  • Author(s): 野村収作
  • Journal Title: 第15回日本行動医学会学術総会資料 Pages: pp.26
• [Journal Article] 色がホルモン・免疫系に及ぼす影響 (2009)
  • Author(s): 野村収作
  • Journal Title: 日本感性工学会第5回春季大会資料 12H-08 Pages: pp.1-2
• [Journal Article] 唾液バイオマーカーによるストレス・リラックス評価,感性評価 (2009)
  • Author(s): 野村収作
  • Journal Title: 感性価値創造に向けた人間工学的アプローチの可能性に関する調査研究, 財団法人 企業活力研究所(委託先:社団法人 人間生活工学研究センター) 付録 Pages: pp.1
  • Peer Reviewed
• [Journal Article] Webサーフィンが生体に及ぼす影響に関する研究-生体化学物質による客観評価の試み (2008)
  • Author(s): 野村収作, 田中秀典, 水野統太, 野澤昭雄, 長島知正, 井出英人
  • Journal Title: 電子情報通信学会和文誌D J-91D(4) Pages: pp.1158-1167
  • Peer Reviewed
• [Journal Article] 脳波による錯視図形認知に関する生理学的研究 (2008)
  • Author(s): 野村収作, 佐々木俊太郎, 北神慎司, 長島知正, 樋脇治
  • Journal Title: 日本感性工学会誌 8(1) Pages: pp.175-183
  • Peer Reviewed
• [Journal Article] The effect of Prolonged Mental Stress under Graduation Examination on Salivary Immunoglobulin A (2008)
  • Author(s): Shusaku Nomura and Tsutomu Kamei
  • Journal Title: in 10th International Congress of Behavioral Medicine Abstract book Pages: pp.216
  • Peer Reviewed
• [Journal Article] Estimation of the Workload with Visual Display Terminal by Salivary Immune Substance (2008)
  • Author(s): Shusaku Nomura
  • Journal Title: in Proceedings of 2008 IEEE Conference on Soft Computing in Industrial Applications Pages: pp.222-227
  • Peer Reviewed
• [Journal Article] An Application of Rough Set Analysis to a Psycho-physiological Study - Assessing the Relation between Psychological Scale and Immunological Biomarker (2008)
  • Author(s): Shusaku Nomura and Yasuo Kudo
  • Journal Title: in Proceedings of Joint 4th International Conference on Soft Computing and Intelligent Systems and 9th International Symposium on advanced Intelligent Systems Pages: pp.232-237
  • Peer Reviewed
• [Journal Article] The Difference in Stress Induced Secretion of an Immune Substance by the Schedule of an Intermittent Mental Workload (2008)
  • Author(s): Shusaku Nomura, Tota Mizuno, Akio Nozawa, Hirotoshi Asano, and Hideto Ide
  • Journal Title: in Proceedings of The 2008 IEEE International Conference on Systems, Man and Cybernetics Pages: pp.137-142
  • Peer Reviewed
• [Journal Article] A Study of Brain Potential on the Perception of Muler-Lyer Illusionary Figures (2008)
  • Author(s): Shusaku Nomura, Shuntaro Sasaki, and Osamu Hiwaki
  • Journal Title: in Proceedings of The Second International Conference on Kansei Engineering & Affective Systems Pages: pp.105-110
  • Peer Reviewed
• [Journal Article] 快・不快評価指標としての唾液分泌物質の特性 (2008)
  • Author(s): 野村収作
  • Journal Title: 日本感性工学会第4回春季大会資料 D3-06 Pages: pp.1-4
• [Journal Article] 唾液中免疫グロブリンによるWebサーフィンのストレス評価 (2008)
  • Author(s): 野村収作, 藤田将輝
  • Journal Title: 日本感性工学会第4回春季大会資料 F-14 Pages: pp.1
• [Journal Article] バイオマーカーによるバイオフィードバック研究へのアプローチ (2008)
  • Author(s): 野村収作
  • Journal Title: 第36回日本バイオフィードバック学会学術大会資料 Pages: pp.36
• [Journal Article] Effect of the Relief from Chronic Stress During Graduation Examination on Salivary Biomarkers (2008)
  • Author(s): Shusaku Nomura, Hideki Ohira, and Tsutomu Kamei
  • Journal Title: 第10回日本感性工学会大会資料 22I-05 Pages: pp.1-6
  • Peer Reviewed
• [Journal Article] 唾液バイオマーカーによる快・不快評価 (2008)
  • Author(s): 野村収作
  • Journal Title: 第10回日本感性工学会大会資料 P02-04 Pages: pp.1
• [Journal Article] The Integration of Salivary Immunoglobulin A by the Repetitive Stressful Task (2007)
  • Author(s): Shusaku Nomura, Tota Mizuno, Akio Nozawa, and Hideto Ide
  • Journal Title: in Proceedings of The 29th Annual Conference of the Cognitive Science Society Pages: pp.1349-1354
  • Peer Reviewed
• [Journal Article] Quantitative Estimation of illusionary band on the Muller-Lyer illusion (2007)
  • Author(s): Shusaku Nomura, Shuntaro Sasaki, Tomomasa Nagashima, and Osamu Hiwaki
  • Journal Title: in Proceedings of The 29th Annual Conference of the Cognitive Science Society Pages: pp.1827
  • Peer Reviewed
• [Journal Article] Evaluation of Human Stress with Salivary Alpha-amylase (2007)
  • Author(s): Shusaku Nomura, Bo Zhao, and Kazuto Yamagishi
  • Journal Title: in Proceedings of The 29th Annual Conference of the Cognitive Science Society Pages: pp.1828
  • Peer Reviewed
• [Journal Article] A Pilot Study on the Effect of the Odor of Isovaleric Acid and Japanese Cypress on Human Secretion of Immune and Endocrine Substances (2007)
  • Author(s): Shusaku Nomura
  • Journal Title: n Proceedings of The Third International Symposium on Humanized Systems Pages: pp.41-44
  • Peer Reviewed
• [Journal Article] On Possibility of Assessing Mental State Including Kansei by DNA Microarray (2007)
  • Author(s): Tomomasa Nagashima, Hikaru Mitsubayashi, Hidenori Tanaka, and Shusaku Nomura
  • Journal Title: in Proceedings of The Third International Symposium on Humanized Systems Pages: pp.170-172
• [Journal Article] 脳波による錯視図形認知に関する脳生理研究 (2007)
  • Author(s): 野村収作, 佐々木俊太郎, 北神慎司, 長島知正, 樋脇治
  • Journal Title: 第8 回日本感性工学会資料 P25 Pages: pp.1-7
  • Peer Reviewed
• [Journal Article] 卒業研究による長期的なストレスが生体内分泌に与える影響 (2007)
  • Author(s): 野村収作
  • Journal Title: 第8 回日本感性工学会資料 B59 Pages: pp.1-8
  • Peer Reviewed
• [Journal Article] 心的ストレス課題に対する生体内分泌指標の動態調査 (2007)
  • Author(s): 野村収作, 水野統太, 野澤昭雄, 井出英人
  • Journal Title: 第24 回日本認知科学会資料 Pages: 第24 回日本認知科学会資料
  • Peer Reviewed
• [Journal Article] 卒業研究による長期的なストレスが生体内分泌に与える影響
  • Author(s): 野村収作
  • Journal Title: 日本感性工学会誌 8(4) Pages: 8 pages, in press
  • Peer Reviewed
• [Journal Article] An Application of Rough Set Analysis to a Psycho-physiological Study - Assessing the Relation between Psychological Scale and Immunological Biomarker
  • Author(s): Shusaku Nomura and Yasuo Kudo
  • Journal Title: Journal of Advanced Computational Intelligence and Intelligent Informatics 13(4) Pages: 8 pages, in press
  • Peer Reviewed
• [Journal Article] Salivary Cortisol as a new Biometric for a Mild Mental Workload
  • Author(s): Shusaku Nomura, Tota Mizuno, Akio Nozawa, Hirotoshi Asano, and Hideto Ide
  • Journal Title: in Proceedings of International Multi-Conference on Biometrics and Kansei Engineering Pages: 6 pages, in press
  • Peer Reviewed
• [Journal Article] Anticipatory Processing in the Brain on the Perception of Muller-Lyer Illusionary Figures - A Brain Potential Study
  • Author(s): Shusaku Nomura, Shuntaro Sasaki, Masato Hirakawa, and Osamu Hiwaki
  • Journal Title: in Proceedings of 9th International Conference on Computing Anticipatory Systems
• [Journal Article] Eliminating the Embedded Relationships in the Questionnaires in an Epidemiological Study Using the Genetic Algorithm
  • Author(s): Shusaku Nomura, Santoso Handri, C.M. Althaff Irfan, Sanae Fukuda, Emi Yamano, and Yasuyoshi Watanabe
  • Journal Title: in Proceedings of 9th International Conference on Computing Anticipatory Systems
• [Journal Article] 色が人間の免疫・内分泌系に及ぼす影響に関する統合評価研究
  • Author(s): 野村収作
  • Journal Title: 第27回日本生理心理学会大会資料 106 Pages: 1 pages, in press
• [Presentation] Anticipatory Processing in the Brain on the Perception of Muller-Lyer Illusionary Figures - A Brain Potential Study (2009)
  • Author(s): Shusaku Nomura, Shuntaro Sasaki, Masato Hirakawa, and Osamu Hiwaki
  • Organizer: 9th International Conference on Computing Anticipatory Systems
  • Place of Presentation: Belgium
  • Year and Date: 20090800
• [Presentation] Eliminating the Embedded Relationships in the Questionnaires in an Epidemiological Study Using the Genetic Algorithm (2009)
  • Author(s): Shusaku Nomura, Santoso Handri, C.M. Althaff Irfan, Sanae Fukuda, Emi Yamano, and Yasuyoshi Watanabe
  • Organizer: 9th International Conference on Computing Anticipatory Systems
  • Place of Presentation: Belgium
  • Year and Date: 20090800
• [Presentation] Salivary Cortisol as a new Biometric for a Mild Mental Workload (2009)
  • Author(s): Shusaku Nomura, Tota Mizuno, Akio Nozawa, Hirotoshi Asano, and Hideto Ide
  • Organizer: International Multi-Conference on Biometrics and Kansei Engineering
  • Place of Presentation: Poland
  • Year and Date: 20090600
• [Presentation] 色が人間の免疫・内分泌系に及ぼす影響に関する統合評価研究 (2009)
  • Author(s): 野村収作
  • Organizer: 第27回日本生理心理学会大会
  • Place of Presentation: 京都
  • Year and Date: 20090500
• [Presentation] 色がホルモン・免疫系に及ぼす影響 (2009)
  • Author(s): 野村収作
  • Organizer: 日本感性工学会第5回春季大会
  • Place of Presentation: 大阪
  • Year and Date: 20090300
• [Presentation] ストレスバイオマーカの現在:PNEI指標の測定と課題 (2009)
  • Author(s): 野村収作
  • Organizer: 第15回日本行動医学会学術総会
  • Place of Presentation: 大阪
  • Year and Date: 20090200
• [Presentation] A Study of Brain Potential on the Perception of Muler-Lyer Illusionary Figures (2008)
  • Author(s): Shusaku Nomura, Shuntaro Sasaki, and Osamu Hiwaki
  • Organizer: The Second International Conference on Kansei Engineering & Affective Systems
  • Place of Presentation: Niigata
  • Year and Date: 20081100
• [Presentation] The Difference in Stress Induced Secretion of an Immune Substance by the Schedule of an Intermittent Mental Workload (2008)
  • Author(s): Shusaku Nomura, Tota Mizuno, Akio Nozawa, Hirotoshi Asano, and Hideto Ide
  • Organizer: The 2008 IEEE International Conference on Systems, Man and Cybernetics
  • Place of Presentation: Singapore
  • Year and Date: 20081000
• [Presentation] An Application of Rough Set Analysis to a Psycho-physiological Study - Assessing the Relation between Psychological Scale and Immunological Biomarker (2008)
  • Author(s): Shusaku Nomura and Yasuo Kudo
  • Organizer: Joint 4th International Conference on Soft Computing and Intelligent Systems and 9th International Symposium on advanced Intelligent Systems
  • Place of Presentation: Nagoya
  • Year and Date: 20080900
• [Presentation] 唾液バイオマーカーによる快・不快評価 (2008)
  • Author(s): 野村収作
  • Organizer: 第10回日本感性工学会大会
  • Place of Presentation: 東京,
  • Year and Date: 20080900
• [Presentation] Effect of the Relief from Chronic Stress During Graduation Examination on Salivary Biomarkers (2008)
  • Author(s): husaku Nomura, Hideki Ohira, and Tsutomu Kamei
  • Organizer: 第10回日本感性工学会大会
  • Place of Presentation: 東京
  • Year and Date: 20080900
• [Presentation] he effect of Prolonged Mental Stress under Graduation Examination on Salivary Immunoglobulin A (2008)
  • Author(s): Shusaku Nomura and Tsutomu Kamei
  • Organizer: International Journal of Behavioral Medicines
  • Place of Presentation: Tokyo
  • Year and Date: 20080800
• [Presentation] 快・不快評価指標としての唾液分泌物質の特性 (2008)
  • Author(s): 野村収作
  • Organizer: 日本感性工学会第4回春季大会
  • Place of Presentation: 宮城
  • Year and Date: 20080500
• [Presentation] 唾液中免疫グロブリンによるWebサーフィンのストレス評価 (2008)
  • Author(s): 野村収作, 藤田将輝
  • Organizer: 日本感性工学会第4回春季大会
  • Place of Presentation: 宮城
  • Year and Date: 20080500
• [Presentation] Estimation of the Workload with Visual Display Terminal by Salivary Immune Substance (2008)
  • Author(s): Shusaku Nomura and Yasuo Kudo
  • Organizer: 2008 IEEE Conference on Soft Computing in Industrial Applications
  • Place of Presentation: Muroran
  • Year and Date: 20080100
• [Presentation] バイオマーカーによるバイオフィードバック研究へのアプローチ (2008)
  • Author(s): 野村収作
  • Organizer: 第36回日本バイオフィードバック学会学術大会
  • Place of Presentation: 大阪
  • Year and Date: 20080100
• [Presentation] 心的ストレス課題に対する生体内分泌指標の動態調査 (2007)
  • Author(s): 野村収作, 水野統太, 野澤昭雄, 井出英人
  • Organizer: 第24回日本認知科学会
  • Place of Presentation: 東京
  • Year and Date: 20070900
• [Presentation] A Pilot Study on the Effect of the Odor of Isovaleric Acid and Japanese Cypress on Human Secretion of Immune and Endocrine Substances (2007)
  • Author(s): Shusaku Nomura
  • Organizer: The Third International Symposium on Humanized Systems
  • Place of Presentation: Muroran
  • Year and Date: 20070900
• [Presentation] The Integration of Salivary Immunoglobulin A by the Repetitive Stressful Task (2007)
  • Author(s): Shusaku Nomura, Tota Mizuno, Akio Nozawa, and Hideto Ide
  • Organizer: The 29th Annual Conference of the Cognitive Science Society
  • Place of Presentation: USA
  • Year and Date: 20070800
• [Presentation] Quantitative Estimation of illusionary band on the Muller-Lyer illusion (2007)
  • Author(s): Shusaku Nomura, Shuntaro Sasaki, Tomomasa Nagashima, and Osamu Hiwaki
  • Organizer: The 29th Annual Conference of the Cognitive Science Society
  • Place of Presentation: USA
  • Year and Date: 20070800
• [Presentation] Evaluation of Human Stress with Salivary Alpha-amylase (2007)
  • Author(s): Shusaku Nomura, Bo Zhao, and Kazuto Yamagishi
  • Organizer: The 29th Annual Conference of the Cognitive Science Society
  • Place of Presentation: USA
  • Year and Date: 20070800
• [Presentation] 脳波による錯視図形認知に関する脳生理研究 (2007)
  • Author(s): 野村収作, 佐々木俊太郎, 北神慎司, 長島知正, 樋脇治
  • Organizer: 第9回日本感性工学会
  • Place of Presentation: 東京
  • Year and Date: 20070800
• [Presentation] 卒業研究による長期的なストレスが生体内分泌に与える影響 (2007)
  • Author(s): 野村収作
  • Organizer: 第8 回日本感性工学会
  • Place of Presentation: 東京
  • Year and Date: 20070800