2010 Fiscal Year Final Research Report
Tree structured analysis for oncology research
Project/Area Number |
19700260
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Statistical science
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Research Institution | University of Yamanashi |
Principal Investigator |
SHIMOKAWA Toshio University of Yamanashi, 大学院・医学工学総合研究部, 准教授 (00402090)
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Project Period (FY) |
2007 – 2010
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Keywords | 樹木構造接近法 / がん臨床試験 / アンサンブル学習法 / 多分岐型樹木構造接近法 |
Research Abstract |
In survival analysis, the useful tool for exploration of the factors is tree structured method. Recently, the tree-structured method has been applied to evaluate covariates (e.g., Crowley, 2004). In this research, have propose the multi-split tree structured method based on k-samples generalized rank test statistics. Moreover, we proposed the methodology of data-adaptive multi-split tree structured method, assuming the power-normal distribution as the survival distribution of each terminal node, where power-normal distribution is defined as the distribution specified before the power-normal transformation. Furthermore, We propose some ensemble method, namely rule ensemble method via elastic net and shrinkage boosting trees.
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Research Products
(47 results)
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[Journal Article] Autofluorescence imaging with a transparent hood for detection of colorectal neoplasms: a prospective randomized trial2010
Author(s)
Y.Takeuchi, N.Uedo, R.Ishihara, H.Iishi, T.Kizu, T.Inoue, R.Chatani, N.Hanaoka, T.Taniguchi, N.Kawada, T.Shimokawa, K.Higashino
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Journal Title
GastrointestinalEndoscopy 72(5)
Pages: 1006-1013
Peer Reviewed
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[Journal Article] Efficacy of an Endo-Knife with a Water-Jet Function (Flushknife) for Endoscopic Submucosal Dissection of Superficial Colorectal Neoplasms2009
Author(s)
Takeuchi, Y., Uedo, N., Ishihara, R., Iishi, H., Kizu, T., Inoue, T., Chatani, R., Hanaoka, N., Taniguchi, T., Kawada, N.Higashino K., Shimokawa, T, Tatsuta, M.
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Journal Title
American Journal of Gastroenterology 105
Pages: 314-322
Peer Reviewed
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[Journal Article] Multi-Center Phase II Study for Combination Therapy with Paclitaxel/Doxifluridine to Treat Advanced/Recurrent Gastric Cancer Showing Resistance to S-1 (OGSG 0302)2008
Author(s)
Takiuchi, H., Goto, M., Imamura,H.Furukawa, H., Imano, H., Imamoto, H., Kimura, Y., Ishida, H., Fujitani, K., Narahara, H., Shimokawa, T.
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Journal Title
Japanese Journal of Clinical Oncology
Pages: 81-176
Peer Reviewed
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[Journal Article] Multicenter phase II study of 2 weeks administration with TS-1 followed by 1 week rest against metastatic gastric cancer2007
Author(s)
Imamura, H., Furukawa, H.Iijima, S., Sugihara, S., Tsujinaka, T.Tsukuma, H., Shimokawa, T.
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Journal Title
Hepatogastroenterology 54(79)
Pages: 2167-2171
Peer Reviewed
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[Presentation] Moderate neutoropenia during chemotherapy may predict a more favorable prognosis in advanced gastric cancer2011
Author(s)
T.Kishimoto, H.Imamura, R.Kawabata, C.Fujii, H.Furukawa, Y.Kurokawa, T.Shimokawa, N.Uedo,K.Fujitani, S.Iijima, H.Takiuchi, M.Imano
Place of Presentation
Seoul, Korea.
Year and Date
20110420-20110423
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[Presentation] A randomized controlled phase III trial to evaluate the effect of preoperative enteral immunonutrition on the surgical site infection after total gastrectomy (OGSG0507) Gastrical Cancers Symposum, American Society of Clinical Oncology2011
Author(s)
Y.Kimura, T.Tsujinaka, K.Fujitani, J.Fujita, I.Miyashiro, H.Imamura, K.Kobayashi, Y.Kurokawa, T.Shimokawa, H.Furukawa
Place of Presentation
San Francisco, USA.
Year and Date
20110120-20110123
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[Presentation] A Randomized Controlled Trial of Animicrobial Prophylaxis Infusion after Gastric Cancer Surgery (OGSG0501)2010
Author(s)
Y.Kurokawa, H.Imamura, K.Inoue, Y.Kimura, K.Fujitani, Y.Miyake, J.Matsuyama, M.Tatsumi, T.Shimokawa, H.Furukawa
Organizer
ESMO Congress
Place of Presentation
Milan, Italy.
Year and Date
20101008-20101012
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[Presentation] Phase II study of docetaxel and cisplatin and fluorouracil for metastatic esophageal cancer2010
Author(s)
Y.F.Peng, M.Imano, H.Imamoto, S.Tamura, K.Kobayashi, T.Shimokawa, Y.Kurokawa, H.Takiuchi, T.Tsujinaka, H.Furukawa(2010)
Organizer
2010 Gastrical Cancers Symposum, American Society of Clinical Oncology
Place of Presentation
Orando, USA.
Year and Date
20100122-20100124
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[Presentation] PPhase I study of S-1, cisplatin, and paclitaxel in patients with advanced gastric cancer2010
Author(s)
T.Kishimoto, H.Imamura, Y.Kimura, T.Tsujinaka, M.Imano, Y.Tokunaga, M.Matsuoka, T.Shimokawa, Y.Kurokawa, H.Furukawa.(2010)
Organizer
2010 Gastrical Cancers Symposum, American Society of Clinical Oncology
Place of Presentation
Orando, USA.
Year and Date
20100122-20100124
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[Presentation] Phase II study of weekly paclitaxel as third-line chemotherapy for advanced or recurrent gastric cancer2009
Author(s)
Yoshida, M., Sato, T., Takiuchi, H., Gotoh, M., Iijima, S., Nakae, S., Shimokawa, T., Kurokawa, Y., Hotta, A.and Furukawa, H.
Organizer
OGSG0602, ESMO2009
Place of Presentation
Berlin, Germany.
Year and Date
20090921-20090924
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[Presentation] Phase III Trail of perioperative alone compared with perioperative plus postoperative antimicrobial prophylaxis in gastric cancer surgery (OGSG0501)2009
Author(s)
Y,Kimura, H,Imamura, K,Inoue, K,Fujitani, Y,Miyake, J,Matsuyama, M,Tatsumi, T,Shimokawa, Y,Kurokawa, H,Furukawa.
Organizer
IGCC2009
Place of Presentation
Krakow, Poland
Year and Date
20090610-20090613
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[Presentation] A randomized phase III trial to determine the efficacy of postoperative antimicrobial prophylaxis in gastric cancer surgery (OGSG0501)2009
Author(s)
K.Inoue, H.Imamura, Y.Kimura, K.Fujitani, Y.Miyake, J.Matuyama, M.Tatsumi, T.Shimokawa, Y.Kurokawa, H.Furukawa
Organizer
2009 ASCO Annual Meeting
Place of Presentation
Orland, USA.
Year and Date
20090529-20100602
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[Presentation] A randomized phase II trial of S1 plus irinotecan versus S1 plus paclitaxel in advanced gastric cancer as a first-line treatment (OGSG0402)2009
Author(s)
Fujitani,K., Takiuchi,H., Sugimoto, N., Imamura,H.Iijima,S.Imano,M.Kimura,Y., Shimokawa,T., Kurokawa, Y., Tsujinaka,T.Furukawa, H.
Organizer
2009 Gastrical Cancers Symposium, American Society of Clinical Oncology
Place of Presentation
San Francisco, USA.
Year and Date
20090115-20090117
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[Presentation] Phase I/II study of weekly taxol plus irinotecan for patients with advanced or recurrent gastric cancer (OGSG0104)2007
Author(s)
Imano, M., Peng, Y-F., Imamoto, H., Shiozaki, H., Kobayashi, K.Aoki, T., Furukawa,H.Tujinaka, T.Takiuchi, H., Uedo, F., Imamura, H., Iijima, S., Shimokawa,T., Taguchi, T.
Organizer
7th International Gastric Cancer Congress.
Place of Presentation
Sao Paulo, Brazil.
Year and Date
20070805-20080812
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[Presentation] Multicenter phase II study of anticrobial prophylaxis in low-risk patients undergoing disital gastrectomy for gastric cancer2007
Author(s)
Kishimoto, T., Imamura, H., Iijima, S.Tsujinaka, T.Tukuma, H., Shimokawa, T.and Furukawa, H.
Organizer
7th International Gastric Cancer Congress
Place of Presentation
Sao Paulo, Brazil.
Year and Date
20070805-20080812
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