2009 Fiscal Year Final Research Report
Nucleoid architecture related to RNA molecules
| Project/Area Number |
19770145
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Molecular biology
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| Research Institution | University of Tsukuba |
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Principal Investigator |
OHNIWA Ryosuke University of Tsukuba, 大学院・人間総合科学研究科, 助教 (30447883)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 染色体構築 / 機能 / 分配 |
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| Research Abstract |
The genomic DNA in bacteria is packed into cells as nucleoid, which is composed of genomic DNA, RNAs and proteins. I focused on the regulatory mechanism of the nucleoid structure because its dynamics is closely related to the essential biological processes such as transcription, translation, replication etc. In the present study, I found i) nucleoid structures are sustained by nascent single stranded RNA, ii) the proteins involved in the nucleoid is highly varied in species-specific and environmental-specific manners.
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