2009 Fiscal Year Final Research Report
Studies on the biological activity of furan fatty acids
| Project/Area Number |
19780162
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fisheries chemistry
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| Research Institution | University of Shizuoka |
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Principal Investigator |
WAKIMOTO Toshiyuki University of Shizuoka, 薬学部, 講師 (70363900)
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| Project Period (FY) |
2007 – 2009
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| Keywords | フラン脂肪酸 / ミドリイガイ / 抗炎症活性 |
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| Research Abstract |
Furan fatty acid is known as naturally occurring in various organisms but rare fatty acid. The elucidation of biological activity of furan fatty acid has been limited to antioxidant activity in vitro due to paucity of this fatty acid. In this study, isolation and semi-synthesis of this fatty acid were established, which enable us to disclose more potent anti-inflammatory activity of furan fatty acid than that of EPA.
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[Journal Article] Binding affinity of tea catechins for human serum albumin: characterization by high-performance affinity chromatography with immobilized albmin column.2010
Author(s)
T. Ishii, K. Minoda, M. -J. Bae, T. Mori, Y. Uekusa, T. Ichikawa, Y. Aihara, T. Furuta, T. Wakimoto, T. Kan, T. Nakayama
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Journal Title
Mol. Nutr. Food Res. 54
Pages: 1-7
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[Journal Article] Structure-activity relationship study onα1 adrenergic receptor antagonists from beer.2009
Author(s)
T. Wakimoto, M. Nitta, T. Chiba, Y. Yiping, K. Tsuji, T. Kan, H. Nukaya, M. Ishiguro, M. Koike, Y. Yokoo, Y. Suwa
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Journal Title
Bioorg. Med. Chem. Lett. 19
Pages: 5905-5908
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