2009 Fiscal Year Final Research Report
Pathophysiology and Hemodynamics of Cerebral aneurysms
| Project/Area Number |
19791010
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | The University of Tokyo (2009)
Jichi Medical University (2007-2008) |
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Principal Investigator |
SHOJIMA Masaaki Jichi Medical University, 医学部附属病院, 助教 (80376425)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 脳動脈瘤 / 血行力学 / 流体力学 / シミュレーション |
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| Research Abstract |
In this research, 82 unruptured cerebral aneurysms were followed with catheter-based 3D rotational angiography, and among them, blister formation was documented in 4 aneurysm during the 10.1 months observation. Three of them could be analyzed here to characterize the hemodynamic features associated with the blister formation. Blister formation occurred at the area of low shear magnitude and high shear gradient. Our findings would contribute to reveal the hemodynamic features leading to the aneurysm progression and provide the basis of the aneurysm treatment via flow alteration.
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