2021 Fiscal Year Final Research Report
The Xanthomonas effector modulate defense responses in nucleus of rice
| Project/Area Number |
19K06061
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 39040:Plant protection science-related
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| Research Institution | Kindai University |
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Principal Investigator |
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| Project Period (FY) |
2019-04-01 – 2022-03-31
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| Keywords | エフェクター / 植物免疫 / イネ |
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| Outline of Final Research Achievements |
The plant diseases represent a major threat to plant health. Successful pathogens are able to secrete or directly deliver effector proteins into the host cytoplasm that modulate host processes for their advantage. XopZ is one of the Xanthomonas oryzae pv. oryzae (Xoo) effector. XopZ suppresses PAMPs induced immunity in rice. To identify the host target of XopZ, I screened proteins that interact with XopZ using a yeast two-hybrid system. I identified the hypothetical protein of unknown functions. To clarify the roles of the hypothetical protein in rice immunity, we generated the hypothetical protein knock-out mutant. The knock-out mutant compromise for the resistance to Xoo.
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| Free Research Field |
植物免疫学
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| Academic Significance and Societal Importance of the Research Achievements |
申請者は、イネの耐病性機構を抑制するために、イネ白葉枯病菌病原菌が獲得してきたエフェクタータンパク質に着目した。これまでに、イネ白葉枯病菌エフェクターXopZの過剰発現イネの解析から、XopZがイネの免疫を阻害することを明らかした。さらに、XopZのイネの標的因子として、機能未知のタンパク質を同定した。この機能未知タンパク質を欠損したイネは、イネ白葉枯病菌に罹病性を示すことから、この機能未知タンパク質がイネの免疫に関与する新規の遺伝子であることが示唆された。
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