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2021 Fiscal Year Final Research Report

Neural mechanism of BMI rehabilitation in monkeys with cerebral infarction

Research Project

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Project/Area Number 19K11384
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59010:Rehabilitation science-related
Research InstitutionKyoto University (2020-2021)
National Center of Neurology and Psychiatry (2019)

Principal Investigator

Tatsuya Umeda  京都大学, 医学研究科, 准教授 (90376723)

Project Period (FY) 2019-04-01 – 2022-03-31
Keywordsマーモセット / 皮質脳波 / 上肢運動
Outline of Final Research Achievements

In order to examine the recovery of upper limb movements in marmosets, it is necessary to conduct appropriate behavioral assessments. Therefore, we developed a reaching task system for BMI rehabilitation and established a training method in which marmosets leave their cages to perform the reaching task in a chair for the behavioral task. As a result, two monkeys were able to perform more than 600 lever pulling movements in 40 minutes.

Free Research Field

神経生理学

Academic Significance and Societal Importance of the Research Achievements

リーチング課題ができるマーモセットのトレーニング手法を開発したことで、上肢運動を制御する神経機構を調べる実験プラットフォームが完成した。この実験プラットフォームを活用した例として、静止時と運動時における感覚応答を記録したところ、一次体性感覚野においてのみ体性感覚情報の調節が行われているというこれまでにない結果を導き出すことができた。

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Published: 2023-01-30  

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