2011 Fiscal Year Final Research Report
Analysis of functional neuron circuits underlying variability and reconstruction of long-term memory
| Project/Area Number |
20243035
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Experimental psychology
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| Research Institution | Kyoto University |
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Principal Investigator |
SAKURAI Yoshio 京都大学, 大学院・文学研究科, 教授 (60153962)
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| Co-Investigator(Renkei-kenkyūsha) |
KANEKO Takeshi 京都大学, 大学院・医学研究科, 教授 (90177519)
AOYAGI Toshio 京都大学, 大学院・医学研究科, 准教授 (90252486)
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| Project Period (FY) |
2008 – 2011
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| Keywords | 長期記憶 / 神経回路 / ニューロン / 海馬 / 前頭前野 / ラット |
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| Research Abstract |
This study intended to experimentally investigate how brains form and use long-term memory, the memory retained for a long time once it is formed. Our concrete procedures were that we first developed original methods of electrophysiological recording and data analysis and then actually recorded and analyzed activities of multiple neurons when animals were forming and using long-term memory. The main results suggest that local circuits of neurons are formed and in active in the hippocampus and the prefrontal cortex when long-term memory has been formed and active. The results also suggest that broad circuits of neurons between the hippocampus and the prefrontal cortex are formed when contents of the memory have changed.
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[Journal Article] Multisensory information facilitates reaction speed by enlarging activity difference between superior colliculus hemispheres in rats.2011
Author(s)
Hirokawa, J., Sadakane, O., Sakata, S., Bosch, M., Sakurai, Y. and Yamamori, T.
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Journal Title
PLoS ONE
Volume: 6(9)
Pages: 1-13
DOI
Peer Reviewed
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[Remarks] (1) 月刊ビジネスアスキー(2010年1月号)『脳の信号を読み取って車椅子や身体を動かせる時代が来る』
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[Remarks] (2) 読売新聞(2009年12月7日)『BMI 脳科学の最前線 <高齢脳>学習能力衰えない 心理学からのアプローチ』
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[Remarks] (3) 日本経済新聞(2009年9月27日)『「脳信号で操作」実用へ前進 患者の生活支援 ロボット連動も』
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[Remarks] (4) 朝日新聞(関西版)(2009年5月4日)『心の働き 実験で解明 老化脳は鍛えられる 京大院・桜井芳雄教授』
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