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2010 Fiscal Year Final Research Report

Molecular Design of Tube Proteins from Bacteriophage T4

Research Project

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Project/Area Number 20350063
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Functional materials chemistry
Research InstitutionKyoto University

Principal Investigator

UENO Takafumi  Kyoto University, 物質ー細胞統合システム拠点, 准教授 (70332179)

Project Period (FY) 2008 – 2010
Keywords超分子 / ナノチューブ / T4ファージ / 蛋白質工学 / 光反応
Research Abstract

In nature, there are a large number of protein assemblies with well-defined and robust nanostructures. However, it remains still difficult to artificially prepare and functionalize such assemblies as nanomaterials. We have synthesized a bio-nanotube consisting of the tubular component proteins of bacteriophage T4 by designing its quaternary structure. The results suggest that the construction of protein assemblies from component proteins of biosupramolecules can be a potential approach for development of bionanomaterials.

  • Research Products

    (44 results)

All 2011 2010 2009 2008 Other

All Journal Article (3 results) Presentation (32 results) Book (8 results) Remarks (1 results)

  • [Journal Article] Dual modification of a triple-stranded b-helix nanotube with Ru and Re metal complexes to promote photocatalytic reduction of CO_22011

    • Author(s)
      N.Yokoi, Y.Miura, C.-Y.Huang, N.Takatani, H.Inaba, T.Koshiyama, S.Kanamaru, F.Arisaka, Y.Watanabe, S.Kitagawa, T.Ueno
    • Journal Title

      Chem.Commum. 47

      Pages: 2074-2076

  • [Journal Article] Construction of Robust Bio-nanotube by Controlled Self-assembly of Component Proteins of Bacteriophege T42010

    • Author(s)
      N.Yokoi, H.Inaba, M.Terauchi, A.Z.Stieg, N.J.M.Sanghamitra, T.Koshiyama, K.Yutani, S.Kanamaru, F.Arisaka, T.Hikage, A.Suzuki, T.Yamane, J.K.Gimzewski, Y.Watanabe, S.Kitagawa, T.Ueno
    • Journal Title

      Smoll(selected as an inside cover picture) 6

      Pages: 1873-1879

  • [Journal Article] 2Construction of an Energy Transfer System in the Bio-nanocup Space by Heteromeric Assembly of gp27 and gp5 Proteins Isolated From Bacteriophage T42009

    • Author(s)
      T.Koshiyama, T.Uen, S.Kanamaru, F.Arisaka, Y.Watanabe
    • Journal Title

      Org.Biomol.Chem. 7

      Pages: 2649-2654

  • [Presentation] 蛋白質集合体形成を利用した機能プログラミング2011

    • Author(s)
      上野隆史
    • Organizer
      新学術領域研究「配位プログラム」第2回公開シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2011-02-04
  • [Presentation] Metal Coordination Designed in Discrete Space of Protein Cages2010

    • Author(s)
      上野隆史
    • Organizer
      The 5th Asian Biological Inorganic Chemistry Conference 2010
    • Place of Presentation
      Kaohsiung, Taiwan
    • Year and Date
      20101102-20101105
  • [Presentation] Metal Coordination Designed in Discrete Space of Protein Assembly2010

    • Author(s)
      上野隆史
    • Organizer
      8^<th> China-Japan Joint Symposium on Metal Cluster Compounds
    • Place of Presentation
      Xi'an, China
    • Year and Date
      20100810-20100813
  • [Presentation] Catalytic Reactions Designed using Protein Scaffolds from Artificial Enzymes to Protein Nanocage Reactors2010

    • Author(s)
      上野隆史
    • Organizer
      NIMS 2010 Conference
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      20100712-20100714
  • [Presentation] Nanotube Architectures Designed from Component Proteins of Bacteriophage T42010

    • Author(s)
      上野隆史
    • Organizer
      5^<th> International Symposium on Macrocyclic & Supramolecular Chemistry
    • Place of Presentation
      Nara, Japan
    • Year and Date
      20100606-20100610
  • [Presentation] 蛋白質微粒子の機能化2010

    • Author(s)
      上野隆史
    • Organizer
      第90回日本化学会春季年会(特別企画「ナノ粒子の深化と応用」)
    • Place of Presentation
      大阪
    • Year and Date
      20100326-20100329
  • [Presentation] Molecular Functions Designed in Protein Nanocage Assemblies2010

    • Author(s)
      上野隆史
    • Organizer
      The 3rd Annual Protein and Peptide Conference (PepCon-2010)
    • Place of Presentation
      at Beijing International Convention Center, Beijing, China
    • Year and Date
      20100321-20100323
  • [Presentation] Bio-hybrid Meso-scale materials for Supramolecular Coordination Chemistry2010

    • Author(s)
      上野隆史
    • Organizer
      Session 173 (Molecular Design in Bioinorganic Chemistry), Pacifichem 2010
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2010-12-20
  • [Presentation] Metal Complexes Functionalized on Tubular Protein Architectures2010

    • Author(s)
      上野隆史
    • Organizer
      Session 164 (Self-assembly and Coordination Chemistry) Pacifichem
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2010-12-18
  • [Presentation] 材料化学を指向した蛋白質分子設計2010

    • Author(s)
      上野隆史
    • Organizer
      分子科学研究所所長招聘研究会「2020年の物質分子科学を語る」
    • Place of Presentation
      岡崎
    • Year and Date
      2010-12-01
  • [Presentation] Bio-hybrid Meso-scale materials for Supramolecular Coordination Chemistry" UdS-Japanese JEPS Symposium on Supramolecular Nanomaterials Science2010

    • Author(s)
      上野隆史
    • Organizer
      Institut de Science et d'Ingenierie Supramolecularies (ISIS)
    • Place of Presentation
      France
    • Year and Date
      2010-10-29
  • [Presentation] 蛋白質を駆使した精密無機化学への挑戦2010

    • Author(s)
      上野隆史
    • Organizer
      京都大学化学研究所講演会
    • Place of Presentation
      宇治
    • Year and Date
      2010-10-12
  • [Presentation] Coordination chemistry of porous protein crystals2010

    • Author(s)
      上野隆史
    • Organizer
      60^<th> Anniversary Conference on Coordination Chemistry in Osaka
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2010-09-28
  • [Presentation] 蛋白質集合体を用いたメゾ分子構造体の機能化2010

    • Author(s)
      上野隆史
    • Organizer
      第4回バイオ関連化学シンポジウム「明日を拓くバイオ関連化学」
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
  • [Presentation] 巨大蛋白質の合理的反応場設計2010

    • Author(s)
      上野隆史
    • Organizer
      第4回日本化学会関東支部大会
    • Place of Presentation
      筑波
    • Year and Date
      2010-08-30
  • [Presentation] 巨大蛋白質の配位化学2010

    • Author(s)
      上野隆史
    • Organizer
      第23回生物無機化学夏期セミナー
    • Place of Presentation
      河口湖
    • Year and Date
      2010-08-29
  • [Presentation] 巨大蛋白質を用いた分子機能空間構築への挑戦2010

    • Author(s)
      上野隆史
    • Organizer
      神奈川大学学術フロンティア「機能物質創成を目指す化学空間の設計と制御」
    • Place of Presentation
      横浜
    • Year and Date
      2010-03-13
  • [Presentation] BIOINORGANIC FUNCTIONS DESIGNED IN NANOCAGED PROTEIN ASSEMBLIES2009

    • Author(s)
      上野隆史
    • Organizer
      Symposium on Advanced Biological Inorganic Chemistry
    • Place of Presentation
      at the Tata Institute of Fundamental Research, Mumbai, India
    • Year and Date
      20091104-20091107
  • [Presentation] Redesigning Protein Spaces for Coordination Chemistry2009

    • Author(s)
      上野隆史
    • Organizer
      14^<th> Intemational Conference on Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya
    • Year and Date
      20090725-20090730
  • [Presentation] Bioinorganic Functions and Structures Designed in Protein Nanocage Assemblies2009

    • Author(s)
      上野隆史
    • Organizer
      Symposium : Inorganic Hybrid Materials ; What are the young scientists preparing?
    • Place of Presentation
      Kyoto
    • Year and Date
      2009-10-08
  • [Presentation] 蛋白質分子フラスコの可能性2009

    • Author(s)
      上野隆史
    • Organizer
      新化学発展協会ライフサイエンス技術部会講演会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-21
  • [Presentation] 新しいメゾ領域科学を目指す蛋白質空間設計2009

    • Author(s)
      上野隆史
    • Organizer
      生体関連サマースクール
    • Place of Presentation
      京都
    • Year and Date
      2009-07-14
  • [Presentation] 蛋白質集合体のナノ空間を利用した化学反応制御2009

    • Author(s)
      上野隆史
    • Organizer
      第25回日本DDS学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-03
  • [Presentation] Re-designing Protein cage architectures for coordination chemistry2009

    • Author(s)
      上野隆史
    • Organizer
      2nd International Symposium for Young Organic Chemistry
    • Place of Presentation
      NIMS, Tsukuba, Japan
    • Year and Date
      2009-03-27
  • [Presentation] 蛋白質複合体を基盤とするナノ触媒設計2009

    • Author(s)
      上野隆史
    • Organizer
      日本化学会ATPシンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2009-03-27
  • [Presentation] 蛋白質をビルディングブロックとする巨大分子集積体の化学2009

    • Author(s)
      上野隆史
    • Organizer
      熊本大学講演会
    • Place of Presentation
      熊本
    • Year and Date
      2009-01-05
  • [Presentation] 精密巨大分子合成を指向した蛋白質の分子設計2008

    • Author(s)
      上野隆史
    • Organizer
      東京工業大学資源化学研究所講演会
    • Place of Presentation
      横浜
    • Year and Date
      2008-12-05
  • [Presentation] 金属イオンを操る蛋白質複合体一その機能と制御2008

    • Author(s)
      上野隆史
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
  • [Presentation] 蛋白質集合体のメゾスケール化学に向けて2008

    • Author(s)
      上野隆史
    • Organizer
      第11回生命化学研究会
    • Place of Presentation
      水上
    • Year and Date
      2008-11-29
  • [Presentation] Integration of Metal Complexes into Viral Component Protein Assemblies2008

    • Author(s)
      上野隆史
    • Organizer
      The IUMRS International Conference in Asia 2008
    • Place of Presentation
      Nagoya
    • Year and Date
      2008-11-11
  • [Presentation] 蛋白質複合体空間を利用した金属触媒反応2008

    • Author(s)
      上野隆史
    • Organizer
      第102回触媒討論会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-09-26
  • [Presentation] Design of Protein Assembly for Coordination Chemisny2008

    • Author(s)
      上野隆史
    • Organizer
      第58回錯体化学討論会
    • Place of Presentation
      金沢
    • Year and Date
      2008-09-20
  • [Book] 配位化学による蛋白質集合体の機能設計金属と分子集合2010

    • Author(s)
      上野隆史
    • Total Pages
      5-23
    • Publisher
      シーエムシー出版
  • [Book] 巨大蛋白質を舞台とする触媒化学現代化学2月号(No.467)2010

    • Author(s)
      上野隆史
    • Total Pages
      54-59
    • Publisher
      東京化学同人
  • [Book] 蛋白質が提供するナノ空間ナノ空間材料の創成と応用2009

    • Author(s)
      渡辺芳人、安部聡、上野隆史
    • Total Pages
      72-79
    • Publisher
      フロンティア出版
  • [Book] 超分子タンパク質内部空間の金属イオン集積超分子金属錯体(錯体化学会選書)2009

    • Author(s)
      安部聡、上野隆史
    • Total Pages
      176-188
    • Publisher
      三共出版
  • [Book] 蛋白質空間錯体Hybrid配位空間の化学2009

    • Author(s)
      渡辺芳人、上野隆史
    • Total Pages
      301-311
    • Publisher
      シーエムシー出版
  • [Book] Artificial Metalloproteins Exploting Vacant Space : Preparation Structures, and Functions(25)2009

    • Author(s)
      安部聡, 上野隆史, 渡辺芳人
    • Total Pages
      25-44
    • Publisher
      Top.Organomet.Chem.
  • [Book] 「架橋化蛋白質結晶の不均一触媒への展開」蛋白質結晶の新展開2008

    • Author(s)
      越山友美、上野隆史
    • Total Pages
      276-288
    • Publisher
      シーエムシー出版
  • [Book] 「ナノ構造蛋白質の内部空間利用」バイオナノプロセス2008

    • Author(s)
      安部聡、上野隆史
    • Total Pages
      62-69
    • Publisher
      シーエムシー出版
  • [Remarks] ホームページ等

    • URL

      http://www.kitagawa.icems.kyoto-u.ac.jp/index.html

URL: 

Published: 2012-01-26   Modified: 2016-04-21  

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