2010 Fiscal Year Final Research Report
Circadian adaptation dynamics of cyanobacterial genome
| Project/Area Number |
20370072
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Molecular biology
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| Research Institution | Waseda University |
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Principal Investigator |
IWASAKI Hideo Waseda University, 理工学術院, 准教授 (00324393)
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| Project Period (FY) |
2008 – 2010
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| Keywords | シアノバクテリア / 概日リズム / 明暗応答 / 環境適応 / Synechococcus |
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| Research Abstract |
Based on microarray analysis combined with molecular genetics, we revealed that more than one third of genes on the genome exhibit significant circadian transcription rhythms with peaking at either subjective dawn or dusk under continuous light conditions. When cells were transferred to the dark, most of gene expression was dramatically suppressed and gave rise to serious discrepancy between transcriptomic and proteomic profiles. Moreover, we found less than 8% of genes on the genome were induced even in the dark, and most of them were under the control of the Kai proteins. Since the kai gene mRNAs were rapidly lost in the dark, our observation revealed the first example of clock-controlled transcription without de novo clock gene expression.
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Research Products
(19 results)
