2010 Fiscal Year Final Research Report
Role of breakfast in food-induced entrainment of mouse circadian clock
| Project/Area Number |
20390065
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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| Research Institution | Waseda University |
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Principal Investigator |
SHIBATA Shigenobu Waseda University, 理工学術院, 教授 (10162629)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 体内時計 / 食事同調 / インスリン / 朝日 / 肝臓 / 代謝 |
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| Research Abstract |
Circadian clock is entrained by light as well as by fixed feeding. In this project we asked which mealtime is key for entrainment, and what kind of food is good entrainment. Breakfast (feeding after long-long starvation) rather than other mealtimes could entrain the liver clock. Among nutrients of food, easily digestible cornstarch had stronger entraining force through high insulin secretion. The preset results suggest us digestible starch for breakfast is good maintenance of circadian rhythm.
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[Journal Article] Attenuated food anticipatory activity and abnormal circadian locomotor rhythms in Rgs16 knockdown mice PLoS One2011
Author(s)
Naoto Hayasaka, Kazuyuki Aoki, Saori Kinoshita, Shoutaroh Yamaguchi, John K. Wakefield, Sachiyo Tsuji-Kawahara, Kazumasa Horikawa, Hiroshi Ikegami, Shigeharu Wakana, Takamichi Murakami, Ram Ramabhadran, Masaaki Miyazawa, Shigenobu Shibata
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Journal Title
Peer Reviewed
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