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2010 Fiscal Year Self-evaluation Report

Field Study on natural medicinal resources in Bangladesh

Research Project

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Project/Area Number 20404004
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Living organism molecular science
Research InstitutionChiba University

Principal Investigator

ISHIBASHI Masami  Chiba University, 大学院・薬学研究院, 教授 (90212927)

Project Period (FY) 2008 – 2010
Keywords天然物化学 / 資源調査 / スクリーニング / 熱帯植物
Research Abstract

本研究では,創薬を目指した天然物の探索研究を強力に展開するために,「バングラデシュ天然薬用資源調査」を行う.バングラデシュは暑熱な気候と肥沃な土壌に恵まれ,熱帯植物を中心として多様な天然薬用資源に富んでいる.しかしながら,天然薬物探索材料としては未だ対象とされているものは少なく,その多くが未開発である
本研究では,バングラデシュ・国立クルナ大学薬学部・教授Samir K.Sadhu博士および公立ジャガナス大学薬学部・准教授FirojAhmed博士,および両博士が所属する両大学研究チームとの密接な共同研究により,熱帯植物を中心にバングラデシュ天然薬用資源の調査ならびにそのバングラデシュ天然薬用資源からの有用天然物の発見およびその有効利用を目指す

  • Research Products

    (14 results)

All 2011 2010 2009 2008 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (4 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Cryptolepine, isolated from Sida acuta, sensitizes human gastric adenocarcinoma cells to TRAIL-induced apoptosis2011

    • Author(s)
      Ahmed, F., Toume, K., Ohtsuki, T., Rahman, M., Sadhu, S.K., Ishibashi, M.
    • Journal Title

      Phytotherapy Research 25

      Pages: 147-150

    • Peer Reviewed
  • [Journal Article] New Hedgehog/GLI signaling inhibitors from Excoecaria agallocha2011

    • Author(s)
      Rifai, Y., Arai, M.A., Sadhu, S.K., Ahmed, F., Ishibashi, M.
    • Journal Title

      Bioorg.Med.Chem.Lett. 21

      Pages: 718-722

    • Peer Reviewed
  • [Journal Article] Search for bioactive natural products from medicinal plants of Bangladesh2010

    • Author(s)
      Ahmed, F., Sadhu, S.K., Ishibashi, M.
    • Journal Title

      J.Nat.Med. 64

      Pages: 393-401

    • Peer Reviewed
  • [Journal Article] Glycosides from Vallaris solanaceae with TRAIL-resistance-overcoming activity2010

    • Author(s)
      Ahmed, F., Sadhu, S.K., Ohtsuki, T., Khatun, A., Ishibashi, M.
    • Journal Title

      Heterocycles 80

      Pages: 477-488

    • Peer Reviewed
  • [Journal Article] Constituents of Amoora cucullata with TRAIL resistance overcoming activity2010

    • Author(s)
      Ahmed, F., Toume, K., Sadhu, S.K., Ohtsuki, T., Arai, M.A., Ishibashi, M.
    • Journal Title

      Org.Biomol.Chem. 8

      Pages: 3696-3703

    • Peer Reviewed
  • [Journal Article] Constituents of Pongamia pinnata isolated in a screening for activity to overcome TRAIL-resistance2010

    • Author(s)
      Minakawa, T., Toume, K., Ahmed, F., Sadhu, S.K., Ohtsuki, T., Arai, M.A., Ishibashi, M.
    • Journal Title

      Chem.Pharm.Bull. 58

      Pages: 1549-1551

    • Peer Reviewed
  • [Journal Article] Constituents from Hoya parasitica and their cell growth inhibitory activity2008

    • Author(s)
      Sadhu, S.K., Khatun, A., Ohtsuki, T., Ishibashi, M.
    • Journal Title

      Planta Medica 74

      Pages: 760-763

    • Peer Reviewed
  • [Presentation] TRAIL-resistance overcoming constituents from a mangrove Amoora cucullata2010

    • Author(s)
      K.Toume, F.Ahmed, T.Ohtsuki, S.K.Sadhu, M.A.Arai, M.Ishibashi
    • Organizer
      13th International Symposium on Marine Natural Products
    • Place of Presentation
      Phuket
    • Year and Date
      2010-10-19
  • [Presentation] TRAILシグナルを介してがん選択的にアポトーシスを誘導する天然物の探索2010

    • Author(s)
      當銘一文, F.Ahmed, 中澤孝文, 大槻崇, 荒井緑, 石橋正己
    • Organizer
      第52回天然有機化合物討論会
    • Place of Presentation
      静岡
    • Year and Date
      2010-09-29
  • [Presentation] Constituents of Amoora cucullata with TRAIL resistance overcoming activity2010

    • Author(s)
      F.Ahmed, K.Toume, S.K.Sadhu, T.Ohtsuki, M.A.Arai, M.Ishibashi
    • Organizer
      日本生薬学会第57年会
    • Place of Presentation
      徳島
    • Year and Date
      2010-09-26
  • [Presentation] Bioactive components from medicinal plants of Bangladesh for abrogating TRAIL-resistance2009

    • Author(s)
      F. Ahmed, T. Ohtsuki, M. Rahman, S. K. Sadhu, K. Toume, M. Ishibashi
    • Organizer
      日本生薬学会第56年会
    • Place of Presentation
      京都
    • Year and Date
      20091003-04
  • [Book] ソレル有機化学2009

    • Author(s)
      村田道雄, 石橋正己, 木越英夫, 佐々木誠(監訳)
    • Total Pages
      854
    • Publisher
      東京化学同人
  • [Remarks] ホームページ

    • URL

      http://www.p.chiba-u.ac.jp/lab/kouzou/

  • [Patent(Industrial Property Rights)] コンブレチン酸A及びB2010

    • Inventor(s)
      石橋正己・中澤孝文・當銘一文・小谷野喬
    • Industrial Property Rights Holder
      千葉大学
    • Industrial Property Number
      特許,特願2010-041883
    • Filing Date
      2010-02-26

URL: 

Published: 2012-02-13   Modified: 2016-04-21  

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