Basic and Clinical research of free dermal fat graft implanted after oncoplastic breast surgery

2012 Fiscal Year Final Research Report

• Project/Area Number: 20591551
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: General surgery
• Research Institution: Kagoshima University
• Principal Investigator: KIJIMA Yuko 鹿児島大学, 医学部・歯学部附属病院, 助教 (60381175)
• Co-Investigator(Kenkyū-buntansha): NATHUGOE Shoji 鹿児島大学, 医歯(薬)学総合研究科, 教授 (70237577) ; YOSHINAKA Heiji 鹿児島大学, 医学部・歯学部付属病院, 准教授 (80191625) ; ISHIGAMI Sumiya 鹿児島大学, 医学部・歯学部付属病院, 講師 (90325803)
• Project Period (FY): 2008 – 2012
• Keywords: 乳癌 / 乳房温存術 / 遊離真皮移植片 / 整容性 / 乳房再建

Research Abstract

As a basic research, we established an experimental rat model implanted FDFG from lateral abdomen on to the surface of the major pectoral muscle we can observe the change over time of the implanted FDFG and reappear. We investigated that avascularization of FDFG occur just after implantation and the stable volume of FDFG wasmaintained by rich blood flow mainly from the surface of the muscle but not from the skin, adjacent parenchymal tissues.

Research Products

• [Journal Article] Immediate breast reconstruction using autologous free dermal fat graft provides better cosmetic results for the patients with upper inner cancerous lesions (2011)
  • Author(s): Kijima Y, Yoshinaka H, Funasako Y, Kaneko K, Hirata M, Mizoguchi T, Ishigami S, Arima H, Nakajo A, Ueno S, Natsugoe S
  • Journal Title: Surgery Today Volume: 41 Pages: 477-489
  • DOI: DOI:10.1007/s00595-010-4307-z
  • Peer Reviewed
• [Journal Article] Immediate reconstruction using a modified thoracodorsal adipofascial cutaneous flap after partial mastectomy (2011)
  • Author(s): Kijima Y, Yoshinaka H, Hirata M, Mizoguchi T, Ishigami S, Arima H, Nakajo A, Ueno S, Natsugoe S.
  • Journal Title: Breast Volume: 20 Pages: 454-457
  • DOI: DOI:10.1016/j.breast.2011.05.001
  • Peer Reviewed
• [Journal Article] Oncoplastic surgery for Japanese patients with centrally located breast cancer: partial resection and reconstruction using local skin-glandular flap (2011)
  • Author(s): Kijima Y, Yoshinaka H, Hirata M, Mizoguchi T, Ishigami S, Nakajo A, Arima H, Kaneko K, Funasako Y, Ueno S, Natsugoe S
  • Journal Title: J US-China Med Sci Volume: 8(3) Pages: 133-137
  • Peer Reviewed
• [Journal Article] Oncoplastic surgery in Japanese patients with breast cancer close to the areola: partial mastectomy using periareolar mammoplasty: a case report (2011)
  • Author(s): Kijima Y, Yoshinaka H, Hirata M, Mizoguchi T, Ishigami S, Nakajo A, Arima H, Ueno S, Natsugoe S
  • Journal Title: Case Report in Surgery Volume: 121985 Pages: 5
  • DOI: DOI:10.1155/2011/121985
  • Peer Reviewed
• [Journal Article] Oncoplastic surgery for Japanese patients with breast cancer of the lower pole (2011)
  • Author(s): Kijima Y, Yoshinaka H, Hirata M Mizoguchi T, Ishigami S, Nakajo A, Arima H, Ueno S, Natsugoe S
  • Journal Title: Surg Today Volume: 41(10) Pages: 1461-1465
  • DOI: DOI:10.1007/s00595-011-4490-6.
  • Peer Reviewed
• [Journal Article] Oncoplastic surgery for Japanese patients with ptotic breasts (2011)
  • Author(s): Kijima Y, Yoshinaka H, Ishigami S, Hirata M, Kaneko K, Mizoguchi T, Nakajo A, Arima H, Funasako Y, Ueno S, Natsugoe S
  • Journal Title: Breast Cancer Volume: 18 Pages: 273-281
  • DOI: DOI:10.1007/s12282-009-0190-0
  • Peer Reviewed
• [Presentation] 乳房縮小固定術の要素を取り入れたOncoplastic Surgery(乳輪縁切開・三日月型真皮弁による固定を行う Peri-areolar mammoplasty) (2012)
  • Author(s): 喜島祐子、他
  • Organizer: 第74回日本臨床外科学会学術集会
  • Place of Presentation: 東京都
  • Year and Date: 2012-11-29
• [Presentation] 下垂乳房乳癌症例に対する乳房小固定術の要素を取り入れたOncoplastic Breast Surgery. (2012)
  • Author(s): 喜島祐子、他
  • Organizer: 第20回日本乳癌学会総会
  • Place of Presentation: 熊本市
  • Year and Date: 2012-06-28
• [Presentation] 下垂乳房例のA・C領域乳癌に対する Oncoplastic surgery(spindle-shaped resection) (2011)
  • Author(s): 喜島祐子、他
  • Organizer: 第49回日本癌治療学会学術集会
  • Place of Presentation: 東京都
  • Year and Date: 2011-11-17
• [Presentation] 下垂乳房例の乳癌症例に対する Oncoplastic surgery(乳腺部分切除+乳房縮小固定術) (2011)
  • Author(s): 喜島祐子、他
  • Organizer: 第73回日本臨床外科学会学術集会
  • Place of Presentation: 東京都
  • Year and Date: 2011-11-17
• [Presentation] Oncoplastic Surgery combining partial mastectomy with reduction mammaplasty for Japanese patients with ptotic breasts (2011)
  • Author(s): Kijima Y,et al
  • Organizer: 3rd international meeting of ORBS
  • Place of Presentation: Nottingham
  • Year and Date: 2011-09-26
• [Presentation] Oncoplastic Surgery combining partial mastectomy with reduction mammaplasty for Japanese patients with ptotic breasts (2011)
  • Author(s): Kijima Y,et al
  • Organizer: 4th Internation Surgical Week 2011
  • Place of Presentation: YOKOHAMA
  • Year and Date: 2011-08-28
• [Presentation] Oncoplastic Surgery combining partial mastectomy with reduction mammaplasty for Japanese patients with ptotic breasts (2011)
  • Author(s): Kijima Y,et al
  • Organizer: 13th Milan Breast Cancer Coference.
  • Year and Date: 2011-06-22