2011 Fiscal Year Final Research Report
The analysis of pathological condition in masticatory muscle tendon-aponeurosis hyperplasia using HUMARA assay and immunostaining methods.
| Project/Area Number |
20592344
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Saitama Medical University |
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Principal Investigator |
YODA Tetsuya 埼玉医科大学, 医学部, 教授 (60242210)
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| Co-Investigator(Kenkyū-buntansha) |
SATO Tsuyoshi 埼玉医科大学, 医学部, 講師 (60406494)
SAKATA Yasuaki 埼玉医科大学, 医学部, 講師 (50322425)
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| Project Period (FY) |
2008 – 2011
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| Keywords | 咀嚼筋腱腱膜過形成症 / クローナリティー解析 / 免疫染色 |
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| Research Abstract |
We calculated seven samples in masticatory muscle tendon-aponeurosis hyperplasia(MATAPHY). We found that both Tenomodulin and Smad8 proteins expressed in MATAPHY's tendon and the proliferation of tendon was a polyclonal fashion. We also demonstrated that collagen 6A1 was upregulated in MATAPHY's tendon by using two dimensional electrophoresis system.
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[Journal Article] Proteomic analysis of a masticatory muscle tendon-aponeurosis hyperplasia : a preliminary study using 2D-DIGE system2012
Author(s)
Sato T, Nakamoto A, Hori N, Enoki Y, Fukushima Y, Nakamoto N, Sakata Y, Yamanaka H, Chida D, Abe T, Yoda T
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Journal Title
J Oral Maxillofac Surg Med Pathol
Volume: (in press)
Peer Reviewed
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