2008 Fiscal Year Final Research Report
Bone fatigue damage under single, static, and cyclic loading : Implications for fatigue fracture etiology.
| Project/Area Number |
20700387
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Biomedical engineering/Biological material science
|
|---|
| Research Institution | Kinki University |
|---|
Principal Investigator |
YAMAMOTO Ei Kinki University, 生物理工学部, 准教授 (00309270)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Keywords | バイオメカニクス |
|---|
| Research Abstract |
In the present study, the specimens were obtained from the middiaphysis of bovine femur. We applied the overloads to the specimens singly, cyclically, or statically. Microdamage in bone tissues induced by overloading was observed by a fluorescence microscopy. The growth of microdamage was monitored during the course of mechanical loading tests by the application of a series of fluorescent chelating agents. By sectioning the specimens both transversely and longitudinally, we examined the damage size and monitored how this changes during mechanical loading. Fluorescence microscopic images showed the propagating of microdamage which is labeled with different agents. Both in the transverse and longitudinal directions, microdamage was found to be greater in case of static and cyclic overloading in comparison to that of single overloading. Not only linear microcracks but also diffused microdamage were observed in the all specimens applied to overloading. The linear microcracks and diffused microdamage were dominated in the cyclic-overload and static-overload groups, respectively. These results showed that the bone microdamage accumulation strongly depends on the cycles, durations, and modes of non-destructive compressive overloading. If the damage accumulation at each type of overloading occurs at such a rate that the capacity for bone repair is exceeded, stress fractures may result in bone tissues.
|
