2009 Fiscal Year Final Research Report
A relationship between epithelial sodium absorption and eosinophilic inflammation
| Project/Area Number |
20791214
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
YASUDA Makoto Kyoto Prefectural University of Medicine, 医学研究科, 助教 (60433273)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 好酸球性炎症 / イオン輸送 / 培養細胞 |
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| Research Abstract |
The mechanism of cytokine secretion by IL-4 was investigated in cultured a human nasal polyp epithelial cells. The most secreted cytokine was RANTS, but eotaxin was not detected in our studies. Treatment of 100ng/ml IL-4 significantly increased RANTES secretion, and this activation was observed at 72 hours after treatment.
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