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2009 Fiscal Year Final Research Report

Relationship between prolonged ischemia and rejection in composite tissue allotransplantation

Research Project

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Project/Area Number 20791311
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Plastic surgery
Research InstitutionOita University

Principal Investigator

SHIMIZU Fumiaki  Oita University, 医学部, 助教 (50347027)

Project Period (FY) 2008 – 2009
Keywords組織培養 / 移植学
Research Abstract

Relationship between ischemia time and rejection of transplanted allograft was assessed using Rat composite tissue allo-transplantation model. As the result, clinical observation, histopathological examination and mixed lymphocyte reaction assay revealed that prolonged ischemia increases severity of rejection in skin flap allotransplantation. Higher expression of MHC-II antigen in longer ischemia group might cause these results.

  • Research Products

    (2 results)

All 2010 0

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (1 results)

  • [Journal Article] Prolonged ischemia increases severity of rejection in skin flap allotransplantation in rats2010

    • Author(s)
      Fumiaki Shimizu, et al
    • Journal Title

      Microsurgery 30(2)

      Pages: 132-137

    • Peer Reviewed
  • [Presentation] 同種異系間複合組織移植における組織虚血時間と拒絶反応の関係0

    • Author(s)
      清水史明、佐藤治明、加藤愛子、種子田紘子、佐藤精一、藤原作平、片桐一元、岡本修
    • Organizer
      第16回日本形成外科学会基礎学術集会
    • Place of Presentation
      神戸
    • Year and Date
      00001011

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Published: 2011-06-18   Modified: 2014-03-06  

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