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2022 Fiscal Year Final Research Report

Dissociation and hybridization of cellulose using zwitterionic polypeptides

Research Project

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Project/Area Number 20K05636
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 35020:Polymer materials-related
Research InstitutionKyoto University

Principal Investigator

Tsuchiya Kousuke  京都大学, 工学研究科, 特定准教授 (40451984)

Project Period (FY) 2020-04-01 – 2023-03-31
Keywordsポリペプチド / 双性イオン / セルロース / 酵素 / 細胞壁
Outline of Final Research Achievements

Novel polypeptides containing a zwitterionic structure similar to ionic liquids, which dissolve cellulose crystals, were designed and synthesized by chemoenzymatic polymerization using enzymes. The aqueous solution of the zwitterionic polypeptides effectively dissociated the bundle of cellulose nanocrystals. It was found that the cellulose network in the cell walls of cultured plant cells was dissociated by treatment with the zwitterionic polypeptides.

Free Research Field

高分子化学

Academic Significance and Societal Importance of the Research Achievements

本研究で開発されたzwitterion型ポリペプチドは、不溶不融で成型加工性に乏しいセルロースの結晶を効果的に解離することが可能であり、セルロースの化学構造を改変することなく簡便に加工する技術として産業的に有用性が高い。また、細胞毒性をほとんど示さずに植物細胞壁のセルロースネットワークを緩めることができ、植物細胞への効率的な物質輸送など植物科学分野への応用も期待できる。

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Published: 2024-01-30  

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