2022 Fiscal Year Final Research Report
Control of complicated root canal system of primary teeth: Induction of repair mechanisms on resorbed part of outer root surface and acquisition of tooth root stability.
Project/Area Number |
20K10197
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Review Section |
Basic Section 57070:Developmental dentistry-related
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Research Institution | Hokkaido University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
中村 光一 北海道大学, 歯学研究院, 助教 (50580932)
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Project Period (FY) |
2020-04-01 – 2023-03-31
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Keywords | 乳歯 / 根管治療 / 水酸化カルシウム製剤 / pH / 歯根吸収 / セメント質 / 根管洗浄 |
Outline of Final Research Achievements |
Regarding the root canal treatments, it was showed that the important factors of the control of complicated root canal system of primary teeth were the root canal irrigation with ultrasonic and the root canal medication by calcium hydroxide (Ca(OH)2). In rat root resorption model in animal experiment, we can show the effects of Ca(OH)2 showed inhibition of root outer resorption and occurrence of cementum deposition. We think cementum deposition is one of repair mechanisms on resorbed part. We could construct a root resorption model in cell culture. But we cannot reach the step as to investigate effects of Ca(OH)2 due to bad reproducibility of alkalinity diffusion.
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Free Research Field |
小児歯科学
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Academic Significance and Societal Importance of the Research Achievements |
乳歯の根管治療は、その複雑な根管系により難しいといわれている。今回の研究成果により、難しいといわれている乳歯根管治療の予後向上の可能性が十分といえないが示された。小児における齲蝕は減少傾向にあるとはいえ、根管治療が必要となる重篤な齲蝕や外傷は存在しており、健全な成長発育が望まれる小児において、口腔機能の維持増進は重要な点の一つである。この口腔機能の維持増進は、健全な歯、歯列、咬合が必須であり、その点からも、意義ある結果となった。
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