Exploratory study on effective hospital environment cleaning with a focus on environmental resistorms.

2022 Fiscal Year Final Research Report

• Project/Area Number: 20K10345
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 58010:Medical management and medical sociology-related
• Research Institution: Kyoto University
• Principal Investigator: Nagao Miki 京都大学, 医学研究科, 教授 (80523993)
• Project Period (FY): 2020-04-01 – 2023-03-31
• Keywords: 病院環境 / 薬剤耐性菌

Outline of Final Research Achievements

To combat drug resistance, comprehensive measures need to be taken not only for humans, but also for animals, plants and the environment. This project was designed to investigate the relationship between environmental maintenance methods around water, drug-resistant bacteria and biofilms, which are the basis for resistorm transfer, in a newly constructed hospital ward. The transition of microbiomes and resistorms was identified for patient care environments that were cleaned and maintained using different management methods on different floors. In addition, the contamination of patient rooms where drug-resistant bacteria have actually been detected, when cleaned in a specific manner, was investigated. The results suggest that the bacterial flora and bacteria levels in the water supply depend more on the frequency of use and age of the building than on the cleaning method and the detection of drug-resistant bacteria.

Free Research Field

院内感染対策

Academic Significance and Societal Importance of the Research Achievements

我が国では、シンクやシャワーの汚染に伴う多剤耐性菌のアウトブレイク報告や、配管へのレジオネラ定着による院内感染の事例が報告されている。また、欧米では、カルバペネム耐性腸内細菌科細菌によるアウトブレイクが社会的な問題となっており、環境汚染との関連について多数の報告があるが、定期的なサンプリングを行って清掃法と細菌叢の変遷を確認した研究はなく、学術的に重要な基礎データを得ることができた。本研究成果を元に、企業や清掃業者と連携し、さらなる環境整備の改良につなげることができるようになったという点で社会的な意義も高い。