2023 Fiscal Year Final Research Report
Non-invasive evalution of cerebral collateral flow using virtual vessel occlusion model
| Project/Area Number |
20K15933
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 46030:Function of nervous system-related
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| Research Institution | Saitama Medical University (2021-2023)
Sapporo Medical University (2020) |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2024-03-31
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| Keywords | 機械的血栓回収療法 / 数値流体力学 / 側副血行路 / バルーン閉塞試験 / もやもや病 / 血行再建術 / 血流シュミレーション / 脳梗塞 |
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| Outline of Final Research Achievements |
Blood flow simulation by computational fluid dynamics using CTA images showed that anatomical changes on the donor vessel in may affect postoperative blood flow changes STA-MCA bypass surgery. We also showed that similar simulations might predict the outcome of balloon test occlusion for cerebral large vessls. In addition, the results of treatment for patients with acute large vessl occlusion were shown in terms of posterior circulation occlusion and atherosclerotic lesions, respectively.
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| Free Research Field |
脳神経外科学
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| Academic Significance and Societal Importance of the Research Achievements |
一般に、脳主幹動脈閉塞症による脳梗塞は死亡や重度の後遺症に繋がりやすいことが知られている。主幹動脈閉塞の非侵襲的な血流シミュレーションを行うこと、主幹動脈閉塞患者の治療成績を示すことは、これらの患者の新規の治療法開発や転機改善に繋がる可能性がある。それにより、社会的には医療費の削減などが期待される。
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