2023 Fiscal Year Final Research Report
Cognitive impairment in remitted bipolar disorder
| Project/Area Number |
20K16662
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 52030:Psychiatry-related
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2024-03-31
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| Keywords | 双極性障害 / 認知機能 |
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| Outline of Final Research Achievements |
It was confirmed that subjective cognitive function and objective cognitive function are related during the remission phase of bipolar disorder. Interestingly, it subsequently became clear that subjective cognitive function was more closely related to social functioning than objective cognitive function. Furthermore, studies using event-related potentials have shown that objective cognitive function has a stronger relationship with P300 average amplitude than subjective cognitive function.
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| Free Research Field |
双極性障害における認知機能障害
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| Academic Significance and Societal Importance of the Research Achievements |
近年、症状寛解期における認知機能障害は、社会機能の障害との関連が注目されており、双極性障害の治療ターゲットとして認知機能障害を捉えることが重要と考えられるようになってきた。現在、認知機能障害は、双極性障害患者の機能回復と生活の質を向上させるための新しい治療標的となっている。
本研究は、双極性障害寛解期における認知機能障害をターゲットとした治療法開発に寄与する可能性がある。
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