Design of High-Performance Organocatalysts for the Application to Fine Organic Synthesis

2014 Fiscal Year Final Research Report

• Project/Area Number: 21000006
• Research Category: Grant-in-Aid for Specially Promoted Research
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering; Chemistry
• Research Institution: Kyoto University
• Principal Investigator: MARUOKA Keiji 京都大学, 大学院理学研究科, 教授 (20135304)
• Co-Investigator(Kenkyū-buntansha): KANO Taichi 京都大学, 大学院理学研究科, 講師 (40372560) ; HASHIMOTO Takuya 京都大学, 大学院理学研究科, 助教 (20437198) ; MOTEKI Shin 京都大学, 大学院理学研究科, 特定助教 (10546980)
• Co-Investigator(Renkei-kenkyūsha): SHIRAKAWA Seiji 京都大学, 大学院理学研究科, 特定准教授 (60459865)
• Project Period (FY): 2009 – 2014
• Keywords: 高性能有機触媒 / 精密有機合成 / 塩基触媒 / 酸触媒 / 酸塩基複合触媒 / ラジカル触媒 / 環境調和型 / 不斉変換反応

Outline of Final Research Achievements

The rational design of high-performance organocatalysts has been performed in the research project, which is divided into four main research items consisting of "high-performance base organocatalyst", "high-performance acid organocatalyst", "high-performance polyfunctional acid/base organocatalyst" and "high-performance radical organocatalyst". By using such high-performance organocatalysts, we succeeded to develop a series of new synthetic methodologies including environmentally benign and asymmetric organic transformations.

Free Research Field

化学