2011 Fiscal Year Final Research Report
Mechanisms of neural circuit formation in the ventral telencephalon
| Project/Area Number |
21300124
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neuroscience in general
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| Research Institution | Kochi University |
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Principal Investigator |
HIRANO Shinji 高知大学, 教育研究部・医療学系, 准教授 (80222248)
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| Co-Investigator(Kenkyū-buntansha) |
YURI Kazunari 高知大学, 教育研究部・医療学系, 教授 (10220534)
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| Research Collaborator |
TAKEICHI Masatoshi 理化学研究所, 発生再生科学総合研究センター, グループディレクター
MASUBA Aya 高知大学, 総合人間自然科学研究科, 大学院生
ASAHINA Hiromichi 高知大学, 総合人間自然科学研究科, 大学院生
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| Project Period (FY) |
2009 – 2011
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| Keywords | 神経科学 / 脳・神経 / 発生分化 / 神経回路 / 細胞接着分子 / カドヘリン |
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| Research Abstract |
To reveal molecular mechanisms of neural circuit formation in the ventral telencephalon, we tried to prove importance of striatal axons and to find novel axon guidance molecules in this region. Due to technical problems, we failed to perform experiments on striatal axons. On the other hand, we could show that PlexinA1 and Semaphorin6D did not play major roles in formation of internal capsule and that distribution of protocadherin 9 protein coincided with certain neural circuits, such as auditory system.
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