2011 Fiscal Year Final Research Report
Construction of OMRI scanner for Large Animal Construction of OMRI scanner for Large Animal Construction of OMRI scanner for Large Animal Construction of OMRI scanner for Large Animal
| Project/Area Number |
21300169
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HYODO Fuminori 九州大学, 先端融合医療レドックスナビ研究拠点, 准教授 (10380693)
YASUKAWA Keiji 九州大学, 大学院・薬学研究院, 助教 (80372738)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 大型磁石 / バイオテクノロジー / 生物・生体工学 / 可視化 |
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| Research Abstract |
In vivo oxidation-reduction(redox) state changed in various diseases, such as a lifestyle-related disease. In this research, imaging apparatus of in vivo redox status for large-sized animal was developed. The developed Overhauser enhanced MRI system has more than 20 cm of effective volume and the OMRI performance was examined both in phantom objects and laboratory animals. MRI signal map of the developed system is homogeneous over 20 cm area, showing the system is useful for large-sized objects.
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[Journal Article] Nitroxides prevent exacerbation of indomethacininduced gastric damage in adjuvant arthritis rats2011
Author(s)
Deguchi H, Yasukawa K, Yamasaki T, Mite F, Kinoshita Y, Naganuma T, Sate S, Yamato M, Ichikawa K, Sakai K, Utsumi H, Yamada Kl.
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Journal Title
Free Radic Biol Med
Volume: 51
Pages: 1799-805
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