2012 Fiscal Year Final Research Report
Modification of enzyme functions by integration of conformationalinformation and function and sequence
| Project/Area Number |
21350096
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemistry related to living body
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| Research Institution | Keio University |
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Principal Investigator |
MIYAMOTO Kenji 慶應義塾大学, 理工学部, 准教授 (60360111)
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| Project Period (FY) |
2009 – 2012
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| Keywords | アリールマロン酸脱炭酸酵素 / ラセマーゼ / 機能改変 / 活性向上 / 立体構造 |
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| Research Abstract |
In this application, a novel arylmalonate decarboxylase (AMDase)was used to be a model enzyme. Conformational information on various enzymes isassociated with sequence information. The relativity of the structure and the function witha lot of uncertain po
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