2011 Fiscal Year Final Research Report
In situ component selective determination of elastic modulus of bone tissue without loading.
| Project/Area Number |
21500401
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Hokkaido University |
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Principal Investigator |
SASAKI Naoki 北海道大学, 大学院・先端生命科学研究院, 教授 (40142202)
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| Co-Investigator(Kenkyū-buntansha) |
FURUSAWA Kazuya 北海道大学, 大学院・先端生命科学研究院, 助教 (00510017)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 骨バイオメカニクス / X線回折 / 温度因子 / 弾性率 |
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| Research Abstract |
Elastic modulus of collagen in bone was determined without loading to the specimen by measuring temperature dependence of X-ray diffraction intensity from collagen. In general, diffraction from collagen in bone is superimposed by that from mineral. We prepared bone specimens with mineral fraction one third of native bone. For these specimens, modulus values of collagen several times larger than that of tendon collagen were obtained. Then, reinforcement of collagen in bone by mineral was confirmed and much larger apparent modulus values for bone collagen than those of tendon collagen were deduced.
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