2011 Fiscal Year Final Research Report
A new theory for characterizing hemodynamics in human brain based on near infrared spectroscopy
Project/Area Number |
21560425
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
System engineering
|
Research Institution | Kitami Institute of Technology |
Principal Investigator |
|
Project Period (FY) |
2009 – 2011
|
Keywords | FDTD解析 / 近赤外分光 / 光拡散方程式 / ヒト脳機能計測 / 脳髄液 |
Research Abstract |
Optical pulse propagation analysis in adult heads is described, which is indispensable for diffuse optical tomography determining blood flow and its oxygenation in human brain. Adult heads consist of heterogeneous scattering medium and nonscattering medium. In this new theory, light propagation across the nonscattering region was calculated based on the space invariance of the radiance along a ray path, and FDTD analysis employing new boundary conditions was used to calculate optical propagation in heterogeneous scattering regions. The received light intensity and the mean time of flight dependences on source-detector separation estimated from the time-resolved reflectance of an adult head model are in reasonable agreement with previously reported experimental data and Monte Carlo simulations.
|