2011 Fiscal Year Final Research Report
Modulation of mRNA splicing for the genetic diseases
Project/Area Number |
21591365
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Pediatrics
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Research Institution | Kawasaki Medical School |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
YAMAUCHI Akira 川崎医科大学, 医学部, 准教授 (80372431)
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Project Period (FY) |
2009 – 2011
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Keywords | 小児免疫 / アレルギー / 膠原病学 |
Research Abstract |
The gaol of this research is an analysis of transcription, post-transcription and the modulation of mRNA. This researches clarified transcriptional regulation of the phagocyte NADPH oxidase(J. Immunol. 2011, BBRC 2010) and signal transduction by oxidative stress for the cells(BBRC 2011). This reaearch further developed the method to detect superoxide quantitatively(Tropical Medicine and Health. 2011).
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Research Products
(17 results)
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[Journal Article] Adult-onset hereditary pulmonary alveolar proteinosis caused by a single-base deletion in CSF2RB2011
Author(s)
Takeshi Tanaka, Natsuki Motoi, Yoshiko Tsuchihashi, Ryushi Tazawa, Chinatsu Kaneko, Takahito Nei, Toshiyuki Yamamoto, Tomayoshi Hayashi, Tsutomu Tagawa, Takeshi Nagayasu, Futoshi Kuribayashi, Koya Ariyoshi, Koh Nakata, and Konosuke Morimoto
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Journal Title
J. Med. Genet
Volume: 48
Pages: 205-209
DOI
Peer Reviewed
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