2011 Fiscal Year Final Research Report
The study of new radiation therapy combined with high concentration ascorbic acid as to achieve high tumor local control rate
| Project/Area Number |
21591603
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Hirosaki University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MONNOZEN Satoru 弘前大学, 大学院・保健学研究科, 助教 (20514136)
TERASHIMA Shingo 弘前大学, 大学院・保健学研究科, 助教 (00583733)
HAZAWA Masakatsu 放射線医学総合研究所, 緊急被ばく医療研究センター, 博士研究員 (40622460)
YOSHINO Hironori 弘前大学, 大学院・保健学研究科, 助教 (10583734)
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| Project Period (FY) |
2009 – 2011
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| Keywords | アスコルビン酸 / 放射線治療 / 癌 |
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| Research Abstract |
This study was conducted to examine the utility of the combined use of ascorbic acid (AsA) and radiation in clinical applications. AsA induced cell death and the number of living cells significantly decreased after combined X-ray irradiation and AsA treatment in comparison with that after X-ray irradiation alone in four all cell lines (HL60, HT1080, SAS, A549). This result suggested that the combined X-ray and AsA treatment was effective against cancer cells and the clinical applications should be examined in the future.
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Research Products
(10 results)
