2010 Fiscal Year Final Research Report
Sensing system to detect magnetic nano-particles for magnetic drug delivery
| Project/Area Number |
21760313
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Measurement engineering
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| Research Institution | Toyohashi University of Technology |
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Principal Investigator |
HATSUKADE Yoshimi Toyohashi University of Technology, 大学院・工学研究科, 准教授 (90339713)
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| Research Collaborator |
TORII Yasukuni 豊橋技術科学大学, 工学部, 学生
KANAI Sho 豊橋技術科学大学, 工学部, 学生
HAYASHI Keita 豊橋技術科学大学, 工学部, 学生
KARITANI Akimasa 豊橋技術科学大学, 工学部, 学生
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| Project Period (FY) |
2009 – 2010
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| Keywords | 計測システム / ドラッグデリバリー |
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| Research Abstract |
In this study, we developed a sensing system using ultra-sensitive SQUID magnetic sensors to detect magnetic nano-particles as a component technology for magnetic drug delivery system (MDDS). An array of 3 channel SQUID was installed on the system, to study the magnetic characteristics of magnetic nano-particles, whose diameters were less than 100 nm. An appropriate method to magnetize and detect the magnetic nano-particles was also investigated. As a result, we found that the particles with diameter of 50 nm generated the largest magnetic signal among the tested particles, and that a dc magnetization method was best suited because this method enabled to suppress energy due to the Brownian motion and convection in ferrofluid of 3 micron litter by means of the static magnetic field, and to detect moving particles in a tube.
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