2010 Fiscal Year Final Research Report
Analysis on regulatory mechanisms for endocytosis mediated by membrane-bending proteins
Project/Area Number |
21770211
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Cell biology
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Research Institution | Kobe University |
Principal Investigator |
ITOH Toshiki Kobe University, 大学院・医学研究科, 准教授 (30313092)
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Project Period (FY) |
2009 – 2010
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Keywords | 生体膜 / エンドサイトーシス |
Research Abstract |
Fer, a tyrosine kinase harboring membrane-bending F-BAR domain, was found to be activated in a manner dependent on membrane curvature. It was also revealed that Fer is involved in macropinocytosis mediated by membrane ruffle formation, as well as clathrin-mediated endocytosis for internalization of transferrin receptor.
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Research Products
(13 results)
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[Journal Article] Proteome of acidic phospholipid-binding proteins : Spatial and temporal regulation of coronin 1A by phosphoinositides.2010
Author(s)
Tsujita, K., Itoh, T., Kondo, A., Oyama, M., Kozuka-Hata, H., Irino, Y., Hasegawa, J., Takenawa, T.
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Journal Title
J.Biol.Chem. 285(9)
Pages: 6781-6789
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[Journal Article] Mutation of ARHGAP9 in patients with coronary spastic angina.2010
Author(s)
Takefuji, M., Asano, H., Mori, K., Amano, M., Kato, K., Watanabe, T., Morita, Y., Katsumi, A., Itoh, T., Takenawa, T., Hirashiki, A., Izawa, H., Nagata, K., Hirayama, H., Takatsu, F., Naoe, T., Yokota, M., Kaibuchi, K.
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Journal Title
J.Hum.Genet. 55(1)
Pages: 42-49
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[Journal Article] Dynamic interaction of amphiphysin with N-WASP regulates actin assembly.2009
Author(s)
Yamada, H., Padilla-Parra, S., Park, S.J., Itoh, T., Chaineau, M., Monaldi, I., Cremona, O., Benfenati, F., De Camilli, P., Coppey-Moisan, M., Tramier, M., Galli, T. Takei, K.
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Journal Title
J.Biol.Chem. 284(49)
Pages: 34244-34256
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